Chapters 2,3,4
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show | a neuron that detects changes in the external or internal environment and sends information about these changes to the CNS.
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show | a neuron located within the CNS that controls the contraction of a muscle or the secretion of a gland.
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interneuron | show 🗑
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show | the brain and spinal cord
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peripheral nervous system (PNS) | show 🗑
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show | the cell body of a neuron, which contains the nucleus.
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show | a branched, treelike structure attached to the soma of a neuron; receives information from the terminal buttons of other neurons.
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synapse | show 🗑
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show | the long, thin, cylindrical structure that conveys information from the soma of a neuron to its terminal buttons.
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show | a neuron with one axon and many dendrites attached to its soma.
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show | a neuron with one axon and one dendrite attached to its soma.
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unipolar neuron | show 🗑
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show | the bud at the end of a branch of an axon; forms synapses with another neuron; sends information to that neuron.
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show | a chemical that is released by a terminal button; has an excitatory or inhibitory effect on another neuron.
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show | a structure consisting principally of lipid molecules that defines the outer boundaries of a cell and also constitutes many of the cell organelles.
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cytoplasm | show 🗑
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mitochondria | show 🗑
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show | a molecule of a prime importance to the cellular energy metabolism; its breakdown liberates energy.
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show | a structure in the central region of a cell, containing the chromosomes.
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show | a strand of DNA, with associated proteins, found in the nucleus; carries genetic information.
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show | an active process by which substances are propelled along microtubules that run the length of the axon.
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microtubule | show 🗑
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glia | show 🗑
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show | a glial cell that provides support for neurons of the CNS, provides nutrients and other substances, and regulates the chemical composition of the extracellular fluid.
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show | the process by which cells engulf and digest other cells or debris caused by cellular degeneration.
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show | a type of glial cell in the CNS that forms myelin sheaths.
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myelin sheath | show 🗑
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node of Ranvier | show 🗑
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microglia | show 🗑
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Schwann cell | show 🗑
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blood-brain barrier | show 🗑
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area postrema | show 🗑
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electrode | show 🗑
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microelectrode | show 🗑
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membrane potential | show 🗑
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oscilloscope | show 🗑
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show | the membrane potential of a neuron when it is not being altered by excitatory or inhibitory postsynaptic potentials; approximately -70 mV in the giant squid axon.
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depolarization | show 🗑
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show | an increase in the membrane potential of a cell, relative to the normal resting potential.
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show | the brief electrical impulse that provides the basis for conduction of information along an axon.
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threshold of excitation | show 🗑
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diffusion | show 🗑
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show | an aqueous solution of a material that ionizes -- namely, a soluble acid, base, or salt.
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show | a charged molecule. Cations are positively charged, and anions are negatively charged.
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show | the attractive force between atomic particles charged with opposite signs or the repulsive force between atomic particles charged with the same sign.
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intracellular fluid | show 🗑
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extracellular fluid | show 🗑
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show | a protein found in the membrane of all cells that extrudes sodium ions from and transports potassium ions into the cell.
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ion channel | show 🗑
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voltage-dependent ion channel | show 🗑
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show | the principle that once an action potential is triggered in an axon, it is propogated, without decrement, to the end of the fiber.
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rate law | show 🗑
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show | conduction of action potentials by myelinated axons. The action potential appears to jump from one node of Ranvier to the next.
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postsynaptic potential | show 🗑
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binding site | show 🗑
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ligand | show 🗑
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dendritic spine | show 🗑
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show | the cell membrane opposite the terminal button in a synapse; the membrane of the cell that receives the message.
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synaptic cleft | show 🗑
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show | a small, hollow, beadlike structure found in terminal buttons; contains molecules of a neurotransmitter.
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show | a receptor molecule in the postsynaptic membrane of a synapse that contains a binding site for a neurotransmitter.
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show | an ion channel that opens when a molecule of a neurotransmitter binds with a postsynaptic receptor.
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ionotropic receptor | show 🗑
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show | a receptor that contains a binding site for a neurotransmitter; activates an enzyme that begins a series of events that opens an ion channel elsewhere in the membrane of the cell when a molecule of the neurotransmitter attaches to the binding site.
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G protein | show 🗑
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show | a chemical produced when a G protein activates an enzyme; carries a signal that results in the opening of the ion channel or causes other events to occur in the cell.
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excitatory postsynaptic potential (ESPS) | show 🗑
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show | an inhibitory hyperpolarization of the postsynaptic membrane of a synapse caused by the liberation of a neurotransmitter by the terminal button.
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show | the reentry of a neurotransmitter just liberated by a terminal button back through its membrane, thus terminating the postsynaptic potential.
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show | the destruction of a neurotransmitter by an enzyme after its release -- for example, the destruction of acetylcholine by acetylcholinesterase.
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acetylcholine (ACh) | show 🗑
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acetylcholinesterase (AChE) | show 🗑
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neural integration | show 🗑
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show | a receptor molecule located on a neuron that responds to the neurotransmitter released by that neuron.
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show | the action of a presynaptic terminal button in an axoaxonic synapse; reduces the amount of neurotransmitter released by the postsynaptic terminal button.
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show | the action of a presynaptic terminal button in an axoaxonic synapse; increases the amount of neurotransmitter released by the postsynaptic terminal button.
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show | a naturally secreted substance that acts like a neruotransmitter except that it is not restricted to the synaptic cleft but diffuses through the extracellular fluid.
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peptide | show 🗑
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show | a chemical substance that is released by an endocrine gland and that has effects on target cells in other organs.
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show | a gland that liberates its secretions into the extracellular fluid around capillaries and hence into the bloodstream.
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show | the type of cell that contains receptors for a particular hormone and is affected by that hormone.
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show | a long, complex macromolecule consisting of two interconnected helical strands; along with associated proteins, strands of DNA constitute the chromosomes.
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gene | show 🗑
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cytoskeleton | show 🗑
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postsynaptic membrane | show 🗑
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show | a molecule that controls a chemical reaction, combining two substances or breaking a substance into two parts.
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neuraxis | show 🗑
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show | with respect to the CNS, located near or toward the head.
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show | with respect to the CNS, located near or toward the tail.
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rostral | show 🗑
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caudal | show 🗑
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show | "Toward the back"; with respect to the CNS, in a direction perpendicular to the neuraxis toward the top of the head or hte back.
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ventral | show 🗑
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show | toward the side of the body, away from the middle.
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medial | show 🗑
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show | located on the same side of the body.
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contralateral | show 🗑
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cross section | show 🗑
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frontal section | show 🗑
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show | a slice through the brain parallel to the ground.
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sagittal section | show 🗑
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show | the plane through the neuraxis perpendicular to the ground; divides the brain into two symmetrical halves.
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show | the 3 layers of tisse that encase the CNS: the dura mater, arachnoid membrane, and the pia mater.
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dura mater | show 🗑
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arachnoid membrane | show 🗑
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pia mater | show 🗑
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subarachnoid space | show 🗑
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cerebrospinal fluid (CSF) | show 🗑
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show | one of the hollow spaces within the brain, filled with cerebrospinal fluid.
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show | one of the two ventricles located in the center of the telencephalon.
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third ventricle | show 🗑
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show | a narrow tube interconnecting the third and forth ventricles of the brain, located in the center of the mesencephalon.
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show | the ventricle located between the cerebellum and the dorsal pons, in the center of the metencephalon.
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show | the highly vascular tissue that protrudes into the ventricles and produces cerebrospinal fluid.
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neural tube | show 🗑
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show | a layer of cells that line the inside of the neural tube; contains founder cells that divide and give rise to cells of the CNS.
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cerebral cortex | show 🗑
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radial glia | show 🗑
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show | cells of the ventricular zone that divide and give rise to cells of the CNS.
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show | division of a founder cell that gives rise to two identical founder cells; increases the size of the ventricular zone and hence the brain that develops from it.
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show | division of a founder cell that gives rise to another founder cell and a neuron, which migrates away from the ventricular zone toward its final resting place in the brain.
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show | death of a cell caused by a chemical signal that activates a genetic mechanism inside the cell.
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show | the most rostral of the 3 major divisions of the brain; includes the telencephalon and diencephalon.
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cerebral hemisphere | show 🗑
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subcortical region | show 🗑
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show | a groove in the surface of the cerebral hemisphere, smaller than a fissure.
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show | a major groove in the surface of the brain, larger than a sulcus.
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gyrus | show 🗑
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show | the region of the posterior occipital lobe whose primary input is from the visual system.
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calcarine fissure | show 🗑
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show | the region of the superior temporal lobe whose primary input is from the auditory system.
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show | the fissure that separates the temporal lobe from the overlying frontal and parietal lobes.
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show | the region of the anterior parietal lobe whose primary input is from the somatosensory system.
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show | the sulcus that separates the frontal lobe from the parietal lobe.
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primary motor cortex | show 🗑
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frontal lobe | show 🗑
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show | the region of the cerebral cortex caudal to the frontal lobe and dorsal to the temporal lobe.
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temporal lobe | show 🗑
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show | the region of the cerebral cortex caudal to the parietal and temporal lobes.
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show | those regions of the cerebral cortex that receive information from the regions of primary sensory cortex.
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show | the region of the frontal lobe rostral to the primary motor cortex; also known as the premotor cortex.
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prefrontal cortex | show 🗑
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corpus callosum | show 🗑
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neocortex | show 🗑
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show | phylogenetically old cortex, located at the medial edge ("limbus") of the cerebral hemispheres; part of the limbic system.
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show | a strip of limbic cortex lying along the lateral walls of the groove separating the cerebral hemispheres, just above the corpus callosum.
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limbic system | show 🗑
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show | a forebrain structure of the temporal lobe, constituting an important part of the limbic system; includes the hippocampus proper (Ammon's horn) dentate gyrus, and subiculum.
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show | a structure in the interior of the rostral temporal lobe, containing a set of nuclei; part of the limbic system.
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fornix | show 🗑
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show | a protrusion of the bottom of the brain at the posterior end of the hypothalamus, containing some hypothalamic nuclei; part of the limbic system.
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basal ganglia | show 🗑
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show | an identifiable group of neural cell bodies in the CNS.
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show | a region of the forebrain surrounding the third ventricle; includes the thalamus and the hypothalamus.
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thalamus | show 🗑
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show | an axon of a neuron in one region of the brain whose terminals form synapses with neurons in another region.
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lateral geniculate nucleus | show 🗑
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medial geniculate nucleus | show 🗑
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ventrolateral nucleus | show 🗑
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hypothalamus | show 🗑
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optic chiasm | show 🗑
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anterior pituitary gland | show 🗑
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show | a neuron that secretes a hormone of hormonelike sunstance.
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posterior pituitary gland | show 🗑
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midbrain | show 🗑
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mesencephalon | show 🗑
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show | the dorsal part of the midbrain; includes the superior and inferior colliculi.
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show | protrusions on top of the midbrain; part of the visual system.
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inferior colliculi | show 🗑
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show | the "stem" of the brain, from the medulla to the diencephalon, excluding the cerebellum.
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tegmentum | show 🗑
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show | a large network of neural tissue located in the central region of the brain stem, from the medulla to the diencephalon.
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periaqueductal gray matter | show 🗑
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red nucleus | show 🗑
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substantia nigra | show 🗑
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hindbrian | show 🗑
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cerebellum | show 🗑
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show | the cortex that covers the surface of the cerebellum.
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show | nuclei located within the cerebellar hemispheres; receive projections from the cerebellar cortex and send projections out of the cerebellum to other parts of the brain.
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cerebellar peduncle | show 🗑
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pons | show 🗑
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show | the most caudal portion of the brain; located in the myelencephalon, immediately rostral to the spinal cord.
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spinal cord | show 🗑
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spinal root | show 🗑
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show | a bundle of spinal roots located caudal to the end of the spinal cord.
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show | the anesthesia and paralysis of the lower part of the body produced by injection of a local anesthetic into the cerebrospinal fluid surrounding the cauda equina.
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dorsal root | show 🗑
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ventral root | show 🗑
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spinal nerve | show 🗑
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afferent axon | show 🗑
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show | a nodule on a dorsal root that contains cell bodies of afferent spinal nerve neurons.
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show | an axon directed away from the CNS, conveying motor commands to muscles and glands.
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cranial nerve | show 🗑
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show | the largest of the cranial nerves, conveying efferent fibers of the parasympathetic division of the autonomic nervous system to organs of the thoratic and abdominal cavities.
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show | the protrusion at the end of the olfactory nerve; receives input from the olfactory receptors.
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show | the part of the peripheral nervous system that controls the movement of skeletal muscles or transmits somatosensory information to the CNS.
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autonomic nervous system (ANS) | show 🗑
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show | the portion of the ANS that controls functions that accompany arousal and expenditure of energy.
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show | nodules that contain synapsys between preganglionic and postganglionic neurons of the sympathetic nervous system.
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show | one of a pair of groups of sympathetic ganglia that lie ventrolateral to the vertebral column.
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preganglionic neuron | show 🗑
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postganglionic neuron | show 🗑
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show | the portion of the ANS that controls functions that occur during a relaxed state.
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