Chapter 2 Human Diseases, A Systematic Approach, 8th ed., Zelman
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show | body's ability to resist infectious disease
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show | any foreign substance that is non self
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show | present at birth and provides immediate short-term protection from antigen, physical barriers and chemical barriers (white blood cells, mucus), includes Phagocytes
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Specific Immunity | show 🗑
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show | disease causing microorganisms
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Phagocytes | show 🗑
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show | Phagocytes
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Humoral Immunity | show 🗑
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show | antibodies are proteins produced by white blood cells called B lymphocytes or b cells
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show | defense against viruses, abnormal cells, and other intracellular pathogens, and it is responsible for rejecting tissue grafts and organ transplants. T cells/lymphocytes responsible
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show | Helper T Cell and Cytotoxic T Cells-
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show | divides producing cytotoxic t cells
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show | activated by antigen and divide and produce clones and memory t cells
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show | Humoral Immunity, B Cells, Cell-mediated Immunity, T Cells
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show | IgM and IgE
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IgM | show 🗑
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IgE | show 🗑
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show | Immune system function declines, Thymus atrophies, Fewer T cells
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show | Agglutination reactions, Enzyme immunoassay (EIA), Western blot, Fluorescent antibody techniques, Flow cytometry, C-reactive protein, Erythrocyte sedimentation
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Agglutination reactions | show 🗑
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show | enzyme to label antibody or antigen, widely used
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show | detects antibodies in serum
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show | use antibody labeled with fluorescent molecule to detect antigen
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Flow cytometry | show 🗑
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show | measure general levels of inflammation in body (same as C-reactive protein)
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C-reactive protein | show 🗑
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show | immune system fails to distinguish between self and non self attacks what it sees as non self
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Autoantibodies | show 🗑
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Raynaud's phenomenon | show 🗑
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show | skin joints heart blood lung brain 90% of women most diagnoses between 15-44 y/o idiopathic etiology-Systemic (many body systems involved), Cutaneous (only skin), Drug-induced, Neonatal
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Scleroderma Overview | show 🗑
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Sjögren's Syndrome Overview | show 🗑
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Allergy Overview | show 🗑
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show | Reduction of helper T cells, Increase opportunistic infections
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Hodgkin's Lymphoma overview | show 🗑
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show | Cancer of the lymphocytes
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