MEDSCI 142
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The nervous system *two types* | show 🗑
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PNS | show 🗑
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CNS | show 🗑
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Sensory | show 🗑
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show | -Efferent Neurons -out (1)Somatic (2)Autonomic
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Somatic | show 🗑
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Autonomic | show 🗑
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Alarm responce (immediate action) | show 🗑
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Relaxation (maintenance) | show 🗑
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show | -INCREASED: digestion, salivation
-DECREASED: HR -CONSTRICTION: pupils, bronchi
-vaso dilation
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Stress response | show 🗑
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2 STAGES of stress response | show 🗑
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show | -immediate -sym activation -adrenal medulla sustains>epinephrine>norepinephrine
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show | -slower, longer lasting -hypothal,pit.,andrenal cortex -cortisol production
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show | -autonomic nervous system -involuntary -limbic,hypothal.,s.cord -2 neuron pathways
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ANS pathways | show 🗑
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Effectors | show 🗑
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Raynaud's | show 🗑
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Hormone types | show 🗑
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show | -to receptors -via blood -on distant target cells
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Local hormones (2TYPES) | show 🗑
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Effectors | show 🗑
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show | -excessive symp stim
-emotional stress
-exposure to cold
-chronic vasoconstriction
-ischemia(lack of blood in hands and feet)
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show | -circulating
-local
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show | -to receptors -via blood -on distant target cells
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Local hormones (2TYPES) | show 🗑
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Cholera: toxin | show 🗑
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Lipid soluble Hormones | show 🗑
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show | -no carrier
-binds to receptors on cell surface
-activate Gprotein>adenyl cyclase
-ATP converted to cAMP
-acivates kinases
-P enzymes
-catalyse reactions producing physiological responses
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Hypothalamus-pituitary axis | show 🗑
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show | -releasing norepinephrine & epinephrine into blood stream
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Adrenal gland MEDULLA | show 🗑
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show | -STIMULATED: increase in K+ -releases corticoids (aldosterone)
-ACTION: incr blood Na+ & water, decr. K+}incr blood vol & pressure
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show | -STIMULATED: Ach from pituitary
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Adrenal gland CORTEX stimulation 1 | show 🗑
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Adrenal gland CORTEX stimulated 2 | show 🗑
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Actions of cortisol (seven) | show 🗑
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show | -in muscle fibres -AAs-->blood -used for synthesis of proteins & ATP production
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(2)Gluconeogenesis | show 🗑
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(3)lipolysis | show 🗑
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(4)stress resistance | show 🗑
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(5)vasocontrition | show 🗑
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show | -limits WBC to tissue
-retards tissue repair & wound healing
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(7)Immune Depression | show 🗑
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