Circulatory; SC Bio5
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show | Distribution, regulates temperature, pH levels and fluid volume, protection
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show | Blood is fluid tissue, has a metallic taste because of the iron, viscous, males average more blood than females (5-6L vs 4-5L)
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Composition of Blood | show 🗑
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show | Erythrocytes (RBC), Leukocytes (WBC) and platelets
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Hematocrit | show 🗑
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show | separates Red blood cells and plasma, <1% of whole blood is platelets and leukocytes (WBC)
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Blood Plasma | show 🗑
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show | By attaching to RBC or by dissolving in plasma
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show | Erythrocytes, leukocytes, and platelets. (most survive in the bloodstream for only a few days)
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show | RBC can't since replicate since they have no nucleus. They are produced by cell division in red bone marrow. (1oz of new blood a day)
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Function of RBC-erythrocytes | show 🗑
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Hemoglobin | show 🗑
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Erythropoietin (hormone) | show 🗑
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show | stem cell> committed cell> hemoglobin forms>reticulocyte leaves bone marrow to mature in blood stream, maturing happens in the blood stream
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show | live 120 days, macrophages in spleen, liver and bone marrow destroy RBC, globin breaks it does into amino acids and is reused, heme breaks down bilirubin(yellow) into stercobilin(brown)
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Erythrocyte Disorder: anemia | show 🗑
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show | Only formed element that is a complete cell, make up <1% of blood volume, and unlike RBC who only stay in blood stream, WBC's leave the bloodstream and can travel into tissue. Two types granulocytes and agranulocytes
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Granulocytes | show 🗑
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Neutrophils | show 🗑
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Eosinophils | show 🗑
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Basophils | show 🗑
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Agranulocytes | show 🗑
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show | T lymphocytes destroy infected cells and B lymphocytes produce antibodies
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show | becomes macrophage, activates B and T lymphocytes
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show | Neutrophil, lymphocyte, monocyte, Eosinophil and basophil
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show | cell fragments, plugs damages vessels and initiates blood clotting
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Human blood groups | show 🗑
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show | markers on the surface of a cell (receptors) Ex. Type A cell contains a antigen A
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show | proteins that travel in the plasma that mark foreign blood cells for destruction. Type A cell contains anti-B antibodies
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type AB | show 🗑
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show | No antigens, has anti-A and anti-B antibodies
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RH blood groups | show 🗑
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