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anatomy
Question | Answer |
---|---|
within muscle is innermost connective tissue layerthat surrounds each muscle cell fiber | endomysium |
around muscle: surrounds bundles of muscle fibers called fascicles. dense irregular connective tissue that surrounds whole skeleton | perimysium |
upon muscle: a layer of dense irregular connective tissue that surrounds whole skeletal muscle | epimysium |
___ stimulare muscle fibers to contract | moror neurons |
highly ordered repeating units of myofilaments | sarcomeres |
two strands of ___ form a double helix extending the length of the actin myofilament | F actin (fibrous) |
___: an elongated protein winds along the groove of the F actin double helix | tropomyosin |
___ is composed of 3 subunits: one that binds to actin, a second that binds to tropomyosin, and a third that binds to calcium ions | troponin |
the _____ complex regulates the interaction between active sites on _____, _____ | tropomyosin/troponin complex, G actin, myosin |
___: filamentous network of protein. serves as attatchment for actin myofilaments | Z disk |
from Z disks to ends of thick filaments | I bands |
length of thick filaments | A bands |
region in A band where actin and myosin don't overlap | H zone |
middle of H zone, delicate filaments holding myosin in place | M line |
in muscle fibers, __ and __ bands of parallel myofibrils are aligned | A and I |
elastic chains of amino acids; make muscles extensible and elastic | tetin filaments |
actin myofilaments sliding over myosin to shorten sarcomeres | sliding filament model |
___ system controls contraction through ____ ____ | nervous, action potentials |
ligands are molecules that bind to receptors: ex: neurotransmitters | ligand-gated |
open and close in response to small voltage changes across plasma membrane | voltage-gated |
inside of plasma membrane becomes less negative. if change reaches threshold ___ occurs | depolarization |
return of resting membrane potential. | repolarization |
spread from one location to another. action potential doesnt move along the membrane; new action potential at each successive location | propagate |
number of action potential produced per unit of time | frequency |
___ muscle: voluntary | skeletal |
origin in primary motor ends | coricospinal neurons |
extrapyramidal neurons: ___,___,___,___ | tectospinal, vestibulospinal, rubrospinal, reticulospinal origin |
origin tectal region of midbraine | tectospinal |
originin vestibular nuclei and cerebellum | vestibulospinal |
origin in red nucleus of pons | rubrospinal |
originin reticular formation of brain stem | reticulospinal |
large type A myelinated nerves | spinal motor neurons |
ventral horn of spinal cord | cell bodies |
skeletal muscle fiber at the neuromuscular junction | final synapse |
one sommatic motor neuron and all the skeletal muscle cells it stimulates | motor unit |
one nerve cell supplies on average ___ muscle cells that all contract in unison | 150 |
total strength of contraction depends on how ___ motor units are activated and how ___ the motor units are | how many,large |
___: axon terminal resting in an invagination of the sarcolemma. | synapse. |
neuromuscular junction is made up of :. | presynaptic terminal, synaptic cleft, postsynaptic membrane (motor end plate). |
___: axon terminal with synaptic vesicles. | presynaptic terminal. |
____ blocks release of neurotransmitter at the NMJ so muscle contraction cannot occur | botulinum toxin |
____ is found in improperly canned food | bacteria (clostridum botulinum) |
botulinum toxin: death occurs from paralysis of ____ | diaphragm. |
derived from clostridum botulinum toxin | botox |
plant poison used by s. american indians for poison arrows | curare |
causes muscle paralysis by blocking ACh receptors, flaccid paralysis | curare |
used to relax muscle during surgery | curare |
antichoinesterase agent | neostigmine |
blocks removal of ACh from receptors so strengthens weak muscle contractions of myasthenia gravis | neostigmine |
antidote for curare after surgery is finished | neostigmine |
inhibit Acherase, spastic paralysis of skeletal muscle | organophosphate |
mechanism where an action potential causes muscle fiber contraction | excitation-contraction coupling |
excitation-contraction coupling involves: | sarcolemma, transverse tubules, terminal cisternae, sarcoplasmic reticulum, triad, Ca2+, troponin |