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Anatomy 2401 Ch. 3

Unit 1

TermDefinition
Cytology The study of cells
Squamous Cell Thin, flat, scaly shape, often with a bulge where the nucleus is
Squamous Cell Locations These cells line the esophagus and form the epidermis of the skin
Cuboidal Cell Squarish-looking and equal in width and height
Columnar Cells Distinctly taller than wide
Columnar Cell Locations Inner lining of stomach and intestines
Fusiform Spindle-shaped; elongated with a thick middle and tapered ends (as in smooth muscle cells)
Cytoplasm The fluid between the nucleus and surface membrane
Plasma (Cell) Membrane Proteins and lipids that surround a typical cell
Cytoskeleton Supportive framework of protein filaments and tubules that determine a cell’s shape, organize its contents, direct the movement of materials within the cell, and contribute to movements of the cell as a whole
Organelles Diverse structures that perform various metabolic tasks for the cell
Cytosol (AKA intracellular fluid / ICF) clear gel in which the cytoskeleton, organelles, and inclusions are embedded
Transmembrane proteins Glycoproteins bound to oligosaccharides on the extracellular side of the membrane that are capable of passing completely through the phospholipid bilayer
Peripheral proteins Membrane proteins that do not protrude into the phospholipid layer but adhere to either the inner or outer face of the membrane
Leak channels Protein channel that is always open to allow materials to pass through continually
Gated channels Protein channels that open and close under different circumstances and allow solutes through at some times but not others
Ligand-gated channels Type of gated channel that responds to chemical messengers
Voltage-gated channel Type of gated channel that responds in changes to electrical potential across the plasma membrane
Mechanically gated channel Type of gated channel that that responds to physical stress on a cell such as stretch and pressure
Carriers Transmembrane proteins that bind to glucose, electrolytes, and other solutes and transfer them to the other side of the membrane
Pumps Type of carries that consume ATP in the process of transfer
Microvilli Extensions of the plasma membrane that serve primarily to increase a cell’s surface area best developed in cells specialized for absorption such as the epithelial cells of the intestines and kidneys
Cilia Hairlike processes that function as a cell’s sensory “antenna”
Selectively permeable Allowing some things through but preventing other things. Cell membranes allow nutrients and wastes, but prevent proteins and phosphates from entering or leaving
Passive Transport Requires no energy expenditure by the cell. Includes filtration, diffusion, and osmosis
Active Transport Type of transport that consumes ATP
Carrier-mediated transport type of transport that uses a membrane protein to transport substances from one side of the membrane to the other
Filtration Process in which physical pressures forces fluid through a selectively permeable membrane
Simple diffusion The net movement of particles from a place of high concentration to a place of lower concentration
Osmosis Net flow of water from one side of a selectively permeable membrane to the other
Aquaporins Channel proteins specialized to allow water to pass through a membrane
Nonpermeating solute Solute that cannot pass through the membrane pores because of its size or other properties
Osmotic Pressure hydrostatic pressure required to halt osmosis
Reverse osmosis Process in which a mechanical pressure applied to one side of a system can override osmotic pressure and drive water through a membrane against its concentration gradient
Tonicity The ability of a solution to affect the fluid volume and pressure in a cell
Hypotonic Solution has a lower concentration of nonpermeating solutes than the ICF (cells absorb water, swell, and lyse)
Hypertonic Solution with a higher concentration of nonpermeating solutes than the ICF (cells lose water and shrivel / crenate)
Isotonic Total concentration of nonpermeating solutes is the same as the ICF (no change in cell volume or shape)
Uniport Carrier that only carries one type of solute
Symport Carrier that moves two or more solutes through a membrane simultaneously in the same direction (cotransport)
Antiport Carries that move two or more solutes in opposite directions (countertransport)
Facilitated diffusion Carrier-mediated transport of a solute through a membrane down its concentration gradient
Primary active transport Process in which a carrier moves a substance through a cell membrane up its concentration gradient using energy provided by ATP (ex. sodium-potassium pump)
Endocytosis Vesicular processes that bring matter into a cell
Phagocytosis “Cell eating” — process of engulfing particles such as bacteria, dust, and debris
Pinocytosis “Cell drinking” — process of taking in droplets of ECF containing molecules of some use to the cell
Receptor-mediated endocytosis More selective form of either phagocytosis or pinocytosis
Exocytosis Process of discharging material from a cell
Nucleus Usually the largest organelle which contain’s the cell’s chromosomes and is the genetic control center of cellular activity
Nuclear envelope Double membrane enclosing the nucleus
Nuclear lamina Narrow but densely fibrous zone immediately inside the nuclear envelope
Nucleoplasm Material inside the nucleus
Chromatin Fine threadlike matter composed of DNA and protein and one or more nucleoli where ribosomes are produced
Endoplasmic reticulum System of interconnected channels called cisterns enclosed by a unit membrane
Rough endoplasmic reticulum Areas of ER in which the cisterns are parallel, flattened sacs covered with ribosomes
Smooth endoplasmic reticulum Areas of ER where the cisterns are more tubular, branch more extensively, and lack ribosomes
Ribosomes Small granules of protein and RNA found in the nucleoli, cytosol, mitochondria, and on the outer surfaces of the rough ER and nuclear envelope that “read” coded genetic messages (mRNA) and assemble amino acids into proteins
Golgi complex Small system of cisterns that synthesize carbohydrates and put finishing touches on protein and glycoprotein synthesis
Lysosome Package of enzymes bounded by a membrane which assist in apoptosis, and help digest phagocytized material
Mitochondria Organelles specialized fir synthesizing ATP
Centriole Short cylindrical assembly of microtubules
Major components of a cell Plasma membrane, Cytoplasm, Cytoskeleton, Organelles, Inclusions, and Cytosol
Created by: meghan.snell81
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