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Anatomy 2401 Ch. 4

Unit 1

TermDefinition
Chromatin Fine filamentous material in the interphase nucleus, composed of DNA and associated proteins
Chromosomes A complex of DNA and protein carrying the genetic material of a cell’s nucleus
Centromere Pinched spot joining together two genetically identical, rodlike sister chromatids
Nitrogenous base pairs of DNA Adenine, Thymine and Cytosine, Guanine (ATCG)
Nitrogenous base pairs of RNA Adenine, Uracil and Cytosine, Guanine (AUCG)
Function of DNA Codes for synthesis of RNA and protein
Function of RNA Carries out the instructions in DNA; assembles proteins
Transcription The process of DNA making mRNA
Translation The process of converting the language of nucleotides into the language of amino acids
Transfer RNA (tRNA) A relatively small RNA whose job is to bind a free amino acid in the cytosol and deliver it to the ribosome to be added to a growing protein chain
Messenger RNA (mRNA) RNA “mirror” of DNA which carries the genetic code from the nucleus to the cytoplasm
Ribosomes Little “reading machines” found in the cytosol and on the outside of the rough ER and nuclear envelope
Three Steps of Translation Initiation, elongation, and termination
Where does most translation occur? In the cytoplasm
Where does most transcription occur? In the nucleus
Anticodon Series of three nucleotides complementary to a specific codon of mRNA
Ribosomal ‘A’ site Aminoacyl site — accepts a new amino acids during translation
Ribosomal ‘P’ site Peptidyl site — carries the growing protein
Ribosomal ‘E’ site Where protein ‘e’xits ribosome
Polyribosome Cluster of ribosomes all translating the same mRNA
RNA polymerase Enzyme that binds to DNA and assembles RNA
DNA polymerase Enzyme with molecules that move along each strand of of DNA, read the exposed bases, and arrange “marriages” with complimentary free nucleotides
Chromatin Fine filamentous material in the interphase nucleus, composed of DNA and associated proteins
Chromosomes A complex of DNA and protein carrying the genetic material of a cell’s nucleus
Centromere Pinched spot joining together two genetically identical, rodlike sister chromatids
Nitrogenous base pairs of DNA Adenine, Thymine and Cytosine, Guanine (ATCG)
Nitrogenous base pairs of RNA Adenine, Uracil and Cytosine, Guanine (AUCG)
Function of DNA Codes for synthesis of RNA and protein
Function of RNA Carries out the instructions in DNA; assembles proteins
Transcription The process of DNA making mRNA
Translation The process of converting the language of nucleotides into the language of amino acids
Transfer RNA (tRNA) A relatively small RNA whose job is to bind a free amino acid in the cytosol and deliver it to the ribosome to be added to a growing protein chain
Messenger RNA (mRNA) RNA “mirror” of DNA which carries the genetic code from the nucleus to the cytoplasm
Ribosomes Little “reading machines” found in the cytosol and on the outside of the rough ER and nuclear envelope
Three Steps of Translation Initiation, elongation, and termination
Where does most translation occur? In the cytoplasm
Where does most transcription occur? In the nucleus
Anticodon Series of three nucleotides complementary to a specific codon of mRNA
Ribosomal ‘A’ site Aminoacyl site — accepts a new amino acids during translation
Ribosomal ‘P’ site Peptidyl site — carries the growing protein
Ribosomal ‘E’ site Where protein ‘e’xits ribosome
Polyribosome Cluster of ribosomes all translating the same mRNA
RNA polymerase Enzyme that binds to DNA and assembles RNA
DNA polymerase Enzyme with molecules that move along each strand of of DNA, read the exposed bases, and arrange “marriages” with complimentary free nucleotides
DNA ligase Enzyme that joins together short segments of DNA
Mutations Any change in the structure of a chromosome or DNA molecule, often resulting in a change of organismal structure or function
G1 phase (first gap phase) An interval between cell division and DNA replication. During this time, a cell synthesizes proteins, grows, and carries out preordained tasks for the body
S phase (synthesis phase) Phase in which a cell makes a duplicate copy of its centrioles and nuclear DNA
G2 phase (second gap phase) The interval between DNA replication and cell division. Cell exhibits further growth, makes more organelles, finishes replicating its centrioles, and synthesizes enzymes that control cell division
M phase (mitotic phase) Phase in which a cell replicates its nucleus and then pinches in two to form two new daughter cells
Interphase The time between M phases. Consists of G1, S, and G2
Prophase Mitotic phase in which the nuclear envelope disintegrates and releases the chromosomes into the cytosol. Spindle fibers grow and tug the chromosomes back and forth until they are all midline
Metaphase Mitotic phase in which the chromosomes are aligned on the cell equator. Long microtubules reach out from each centriole to chromosomes and shorter microtubules anchor the assembly to the inside of the plasma membrane at each end of the cell
Anaphase Mitotic phase which begins with an enzyme cleaving sister chromatids from each other into separate daughter chromosomes which migrate to each pole of the cell
Telophase Mitotic phase in which the daughter chromosomes cluster on each side of the cell where the rough ER produces a new envelope for each. Overlaps with cytokinesis
Cytokinesis Division of the cytoplasm into two cells
Created by: meghan.snell81
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