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Nerves 1

TermDefinition
Sensation Sensory organs receive information about the internal and external environments, and transmits messages to the spinal cord and the brain
Integration Brain and spinal cord processes information from sensory organs; "What does this mean? What is the appropriate reaction?"
Response Brain and spinal cord issues commands to effector organs in order to react to the stimulus
Central nervous system Consists of the brain and spinal cord, enclosed by cranium and vertebral column
Peripheral nervous system All of the nervous system except for the brain and spinal cord, composed of nerves and ganglia.
Nerve A bundle of nerve fibers wrapped in fibrous connective tissue
Ganglion A knot-like swelling in a nerve where neuron cell bodies are concentrated
Excitability A universal property of neurons; is able to respond to stimuli
Conductivity A universal property of neurons; neurons respond to stimuli by producing electrical signals that are quickly conducted to other cells at distant locations
Secretion A universal property of neurons; able to secrete a neurotransmitter to stimulate another cell
Afferent Neuron Sensory neurons that conduct responses to the CNS from the sensory organs
Interneuron Neurons in the brain and spinal cord that receives signals from many neurons and carries out integrative function
Efferent Neuron Motor neurons that conduct signals away from the CNS to effector organs
Soma Cell body and control center of the neuron; has a single, centrally located nucleus with large nucleolus
Cytoplasm Contains organelles, numerous inclusions, and an extensive rough ER and cytoskeleton
Cytoskeleton Consists of dense mesh of microtubules and neurofibrils; compartmentalizes rough RE into Nissil Bodies
Neurofibrils Bundles of actin filaments found tin neuron cytoskeleton
Inclusions Glycogen granules, lipid droplets, melanin, and lipofuscin
Lipofuscin A golden brown pigment produced when lysosomes digest worn-out organelles; accumulates with age in neurons
Dendrites Vast number of branches coming from a few thick branches from the soma; primary sites for receiving signals from other neurons
Axon Nerve fiber; originates from the axon hillock on one side of the soma. Unbranched for most of its length, and is specialized for rapid conduction of nerve signals to points remote to soma
Axon collaterals Branches on the axon
Axoplasm The cytoplasm of the axon
Axolemma The plasma membrane of an axon
Myelin sheath Fatty sheaths that enclose the axon, insulating it and speeding up transmissions
Terminal arborization Extensive complex of fine branches that occurs at the distal end of the axon
Synaptic knob Swelling that forms the synapse with the next cell; contains synaptic vesicles full of neurotransmitter
Multipolar neuron The most common neuron, contains one axon and multiple dendrites, and is found in the brain and spinal cord
Bipolar neuron Neuron that contains one axon and one dendrite; found in olfactory cells, retina, and the inner ear
Unipolar neuron Contains a single process leading away from the soma; gathers sensory information from the skin and organs to the spinal cord
Anaxonic neuron Contains many dendrites, but no axon. Helps in visual processes.
Glial cells Cells that support the neurons; outnumbers them by as much as 50 to 1
Oligodendrocyte Glial cell in the CNS that forms the myelin sheath.
Ependymal cell Glial cell in the CNS that secretes and circulates cerebrospinal fluid
Microglia Glial cell in the CNS that are tiny macrophages, helping to defend the CNS from potential pathogens
Astrocyte Glial cell in the CNS; carries out many functions, such as forming the blood brain barrier, forming a supportive network of tissue and converting blood glucose to lactate for nourishment
Nerve growth factors Helps neurons grow and promotes synapse function; secreted by astrocytes
Astrocytosis Sclerosis; when a neuron is damaged, astrocytes form scar tissue and fill the space formerly occupied by the neuron
Schwann cell Glial cell in the PNS that forms the myelin sheath
Satellite cell Glial cell in the PNS that surrounds the neurosomas in ganglia, insulating it. Also has a job in regulating the chemical environment of neurons
Gliomas Brain cancer that originates from a glial cell
Neurilemma Thick outermost coil of the myelin sheath in a peripheral nerve fiber
Nodes of Ranvier Gaps between myelin segments
Internodes Myelin-covered segments from one gap to the next
Initial segment Short section of nerve fiber between the axon hillock and the first glial cell
Trigger zone The axon hillock and the initial segment; plays an important role in initiating a nerve signal
Multiple Sclerosis Destruction of myelin sheath due to an autoimmune attack; nerve conduction disrupted and sensation hampered
Tay-Sachs disease Hereditary disorder of infants of Eastern European Jewish ancestry, where glycolipid GM2 accumulates and disrupts conduction of nerve signals
Mesaxon Neurilemma wrapping of unmyelinated nerve fibers
Created by: Rylyn27463
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