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BMS 250 Lab

Lab 11

TermDefinition
Motor unit composed of a motor neuron and all the muscle fibers that are innervated by that motor neuron; determines difference in force and precision of muscle movement depending on number of motor units activated
Motor unit recruitment the activation of additional motor units to accomplish an increase in contractile strength in a muscle
Muscle twitch a single action potential from a motor neuron will produce a single contraction in the muscle fibers of its motor unit
If a greater number of motor units are activated... then more muscle fibers contract and a greater force is exerted
Electromyogram a test used to record electrical activity of muscles
Latent period Ca2+ released from SR, Ca2+ binds to troponin changing its shape, moving tropomyosin off the binding sites on actin, myosin binds to the active site on actin initiating crossbridge cycling, but no shortening of muscle fibers occurs
Contraction period crossbridgecycling: crossbridge formed by myosinheads attaching toactin, powerstroke (pulling of actin past myosintoward center ofsarcomere by myosinheads), release of myosinhead from actin by binding of ATP, &resetting of myosinhead by ATPhydrolysis
Relaxation period myosin heads release thin filament, Ca2+ levels in sarcoplasm decrease (ion pumps return Ca2+ into SR and gated Ca2= channels in SR close), tropomyosin covers myosin binding site
What happens to the contraction (muscle force) amplitude as the electrical activity increases? it also increases due to recruitment
Where to find latent period time on electromyogram? top right corner (T2-T1)
Where to find force on electromyogram? right middle (V2-V1)
Causes of fatigue decrease in AP due to sodium/potassium imbalances, change in membrane muscle potential, SR Ca2+ leak, Ca2+ reverse, Ca2+ troponin interaction, depletion theories: PCr, ATP, glycogen, accumulation theories: H+, Pi, lactate
Created by: kkade
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