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Lecture Test 3

Dr. Zhou's Ch 24, 25, & 26

QuestionAnswer
Metabolism is best described as: The sum of all chemical reactions that take place in catabolism & anabolism Catabolic- break down large organic molecules, which release the energy that was contained in the chemical bonds Anabolic- joining of smaller molecules into larger ones
What is the most important outcome of cellular respiration? Cellular respiration refers to cells using glucose and converting it into ATP Most important outcome is ATP formation
ATP is: The energy currency of cells, can be used to immediately power molecular machines that support cells, tissues, and organ function
A person becomes hungry after he has NOT eaten for a time because: A drop in blood glucose levels slow down the release of the hormones leptin and insulin. Low levels are detected by the hypothalamus, which releases neuropeptide Y
Uncontrolled ketosis (usually low) ultimately will result in: An abnormally high level of ketone in bodies in the blood is called ketosis. Ketone bodies are acidic and lower the pH of blood. Low blood pH can cause disorientation, coma, and death
Ammonia produced by deamination is converted by the liver into a less toxic substance called: Urea
Which of the following produced the most body heat? Catabolic reactions produce more body heat then anabolic reactions 40% is used in ATP, 60% is released as heat (regulates body temperature)
The principal result of glucose metabolism is the: Formation of ATP through cellular respiration
Basal metabolic rate is a measurement of the body's energy needs when it is in a: Quiet, resting, and fasting state
The formation of glycogen from glucose is called: Glycogenesis
Before fatty acids can be oxidized by means of Krebs cycle, they must be converted into: Acetyl Coenzyme A (Acetyl CoA)
Before fatty acids can be utilized as fuel, they are degraded by beta oxidation to molecules of: Acetyl CoA
Excess protein taken into the body will be: Converted into glucose or triglycerides Excess protein is not excreted by urine or feces, but recycled Converted into fat
Carbon dioxide plus ammonia forms: Urea
Most biological oxidations are: Dehydrogenation reactions
Conversion of NAD1 to NADH and H1 is: A reduction reaction
The function of coenzyme A in glucose metabolism is: To bind with an acetyl group to for Acetyl CoA
The primary significance of the Krebs cycle in terms of ATP production is: The formation of NADH and FADH
Each molecule of Acetyl CoA that enters the Krebs cycle produces how many molecules of carbon dioxide? 2 molecules of Carbon Dioxide per Acetyl CoA molecule
The end products of the complete aerobic oxidation of glucose are: 6 CO2 + 6 H20 + 30 to 32 ATP
Which of the following processes requires oxygen? The Krebs cycle and electron transport chain (both occurs in the mitochondria)
The most common carbohydrate "fuel" for living organisms is: Glucose
Enzymes of the Krebs cycle and electron transport chain are located in the : Mitochondria
Where the glycolysis is carried out in the cell? In the cytosol or cytoplasm
Which statement of catabolism is correct? Catabolism releases energy and are oxidative reactions
Which statement of anabolism is correct? Anabolism uses or absorbs energy and are reduction reactions
Which statement about HDL is NOT correct? Needs to be known: HDL removes excess cholesterol from the blood and sends it to the liver for elimination, considered good cholesterol
Which statement about LDL is NOT correct? Needs to be known: LDL transports cholesterol to cells, deposits cholesterol onto smooth muscle of arteries; can cause coronary artery disease and heart attack
Which of the following is not considered a key molecule of metabolic crossroad: Three key molecules: Glucose-6-phosphate, pyruvic acid, and Acetyl CoA
A process called deamination in the hepatocytes is involved in the catabolism of: Proteins
During the breakdown of glucose, what are the net gain of ATP in anaerobic pathway? 2 ATP (4 are produced but 2 are used)
During the breakdown of glucose, what are the net gain of ATP in aerobic pathway? 30 or 32 ATP
How can energy be obtained from amino acids Deamination of amino acids will allow them to enter the Krebs cycle
Which statement about lipids broken down is correct? Triglycerides will be broken down into glycerol and fatty acids Glycerol can be converted into glucose and fatty acids into Acetyl CoA to enter Krebs cycle
What is gluconeogenesis? Conversion of non-carbohydrate molecules into glucose
Which statement is correct about the regulation of absorptive phase? Metabolism after eating, a rise in blood glucose causes insulin release, causes glucose to enter cells, insulin converts glucose into glycogen in liver, insulin stimulated cells to synthesize triglycerides and proteins, T3 and T4 cause protein synthesis
Which statement is correct about the regulation of postabsorptive phase? Insulin levels lower due to lower blood glucose level. Glucagon & epinephrine cause glycogen (liver) to break down for energy, epinephrine & norepinephrine stimulate lipolysis to make glucose, & cortisol will break down protein to make glucose.
Which is the factor is involved in heat exchange with the environment? Conduction: transfer heat to another object (direct) Convection: transfer heat by movement of fluid between areas of different temps. Radiation: transfer heat to cooler objects around you (not direct) Evaporation: conversion of liquid to vapor
Which of the following is/are characteristic of the kidney? Positioned behind padded layer of fat, inside renal sinus, upper rear portion of abdominal cavity, supplied by renal vein and drained by renal artery
The glomerular membrane differs from a typical capillary membrane in which of the following ways? It has a lot of tiny holes, more permeable to H2O and small molecules, filtration easier, glomerular drained by efferent arteriole
Which of the following mechanisms, if any, exerts the greatest influence towards maintaining homeostasis of total fluid volume? Renal tubular water reabsorption ability
In systemic hypotension,____is secreted; as a result,____will constrict the efferent arterioles leading to increased blood pressure in glomerulus, Renin, Angiotensin 2 (secreted by JGI)
Whenever the plasma glucose concentration exceeds the renal threshold for glucose: Glucose will appear or lost in urine
Place the following in their proper sequence: 1. Release of renin 2. Sodium reabsorption from tubules 3. Formation of angiotensin 2 from angiotensin 1 4. Release of aldosterone 5. Conversion of angiotensinogen to angiotensin 1 CORRECT ORDER: 1, 5, 3, 4, 2
If the glomerular blood pressure is 65 mmHg, the capsular hydrostatic pressure is 12 mmHg, and the colloidal osmotic pressure in the glomerulus approximates 28 mmHg, what is the effective filtration pressure? 65-12-28=25 mmHg
Filtration in the glomerulus is due principally to: Glomerular blood pressure
Which of the following statements is "NOT TRUE" for the ureter? False: Contains skeletal muscle in its wall True: carries urine from the kidney to the urinary bladder
What effect does antidiuretic hormone have on the kidney? Stimulates kidney to reabsorb H2O
Aldosterone: From cortex of adrenal gland, leads to an increase of the crystalloid osmotic pressure of the blood, increase the reabsorption of sodium from the tubular lumen of the nephron
Juxtaglomerular cells would be stimulated to produce renin by? Moderate to severe hemorrhage or seriously dehydrated
An increase in the amount of carbon dioxide in the blood will? Increase the hydrogen ion concentration of the blood
Urination would be increased by: Antidiuretic hormone will be reduced, NAP, drinking lots of water
What would probably occur if the prostate gland had a tumor in its central part? The urethra would be constricted and urine would back up to the bladder
Consumption of alcohol increases urine production by: Inhibiting the release of ADH from the posterior pituitary gland
When a substance in the renal tubules exceeds its threshold: The amount of the substance will be found in the urine
Antidiuretic hormone (ADH) is produced in the: Neurons of the hypothalamus
Potassium secretion into the urine is controlled by: Aldosterone secretion
After the bladder is stretched due to the buildup of urine, nerve impulses pass through the spinal cord to the hypothalamus via the: Lateral spinothalamic tract
Because about 20% of the water in the glomeruli is filtered into the Bowman's Capsule, the ____osmotic pressure of the blood entering the peritubular capillary bed is_____. Relative, increased
An abnormal constituent in the urine is: Protein, glucose, RBCs amino acids
The kidney's control over Na+ excretion is monitored by a hormone called? Aldosterone
The amount of water lost or retained by the body is primarily regulated by: The antidiuretic hormone
Glomerular filtrate is similar to plasma in composition EXCEPT that the filtrate lacks significant amounts of: Proteins
When arterial blood pressures decrease substantially, the glomerular filtration rate: Decreases slightly
The kidneys help to regulate the pH of the body fluids by controlling the: Secretion of hydrogen ions; if more acidic secretes more hydrogen ions
When excessive amounts of water are lost due to sweating or diarrhea: Dehydration --> Production of ADH --> Renin is secreted --> H20 is retained
ADH, a hormone believed to be synthesized by neurons in the hypothalamus, is released into the blood by the posterior pituitary gland, an it Accelerates distal tubule reabsorption of H2O in PCT and collecting duct
The epithelium of the glomerulus is composed of: Fenestrated endothelium
The ion that would have the greatest effect on water movement between body compartments is: Sodium
Microvilli are in the greatest quantity in the: Area of the proximal convoluted tubules (PCT)
The inner (visceral) layer of the glomerular capsule is made of: Podocytes
The liquid which collects in the minor calices of the renal sinus is: Urine
Which has as its main function the "reabsorption of sodium, chloride, amino acids, and about 80% of eventual water reabsorption?" Proximal convoluted tubule (PCT)
The maintenance of a relatively high blood pressure in the glomerulus is related to the fact that: The afferent arteriole is larger than the efferent arteriole, takes blood out of the glomerulus
The hormone ADH functions by affecting what part of the kidney? The collecting duct and Distal convoluted tubule (DCT)
Angiotensin 1 splits from angiotensinogen by the enzymatic action of: Renin
Which of the following is not actively reabsorbed? H2O
The direction of water movement between fluid compartments is determined by: The concentration of solutes or sodium
The primary means of water movement between fluid compartments is: Osmosis, concentration of ions
The thirst center is stimulated by ALL of the following EXCEPT: Stimulate thirst center: Osmos receptors in the hypothalamus, baroreceptors, dry mouth, and angiotensin 2
The primary determinant of body fluid volume is the: Number of sodium and chloride ions lost from the kidneys
A decrease in angiotensin 2 leads to: A decreased blood volume due to increased glomerular filtration rate
In studies of fluid balance, the term water intoxication refers to: Movement of H2O from the interstitial fluid into intercellular fluid due to osmotic pressure created by ion loss
ADH saves water by: Enhancing passive movement of water out of the collecting duct
Extracellular fluids are: High in sodium and low in potassium outside th cell
Excessive intake of drinking of water normally leads to: Reduced ADH secretion and rise in blood pressure
Levels of sodium ions in the extracellular fluid are regulated primarily by: Aldosterone
Levels of potassium ions in the extracellular fluid are regulated primarily by: Aldosterone
The primary intracellular ions are: Potassium, phosphate ions, and protein anions
Protein anions are most abundant in: Cytosol cells
When bicarbonate ion diffuses out of RBCs into plasma, it is usually exchanged with which anion? Hydrogen
Bicarbonate ions acts as a: Weak base
The carboxyl group of an amino acid acts as a buffer for: Excessive hydroxide ions and strong base
Hemoglobin picks up a hydrogen ion when: It releases O2 to tissues
If the blood is acidic, which one of the following would NOT occur? Ammonia would be secreted by the cells of the kidney tubules, sodium ions are taken up by kidneys and hydrogen ions would be excreted the kidneys, more acid will be secreted in the urine
Holding your breath for an extended period of time results in: Respiratory acidosis
In compensating for respiratory alkalosis, the body excretes more: Bicarbonate ions into the urine
An increase in ADH leads to: Insertion of aquaporin-2 channels into principle cell membrane, more water can pass through membrane
The inspiratory center in the medulla oblongata triggers more forceful and frequent contractions of the diaphragm if: Levels of ketone bodies become elevated (blood pH=more basic), blood becomes too acidic the respiratory rate will increase
Hydrogen ions are normally eliminated from the body by: Excretion of urine
A person who has not eaten for a week is probably: Generate ketone bodies, excreting excess hydrogen ions, and generating new bicarbonate ions
Increasing respiratory rate will: Result in an increase in the excretion of excess bicarbonate ions
Uncontrolled diabetes mellitus may lead to metabolic acidosis because: Increased rate of lipolysis and ketogenesis occurs
Which of the following might trigger an increase in the rate of deamination of glutamine by the renal tubule cells as a form of compensation for a pH imbalance? Pulmonary edema
The most abundant buffer intracellular fluid system is: Proteins
Use of laxatives in older people to relieve constipation often results in: Hypokalemia
Edema may result from: Increased blood hydrostatic pressure, lymphatic blockage, and hypoproteined
The level of sodium ions in the blood is controlled by the hormones: Aldosterone, ADP, and ADH
Created by: Mari_Lopez127
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