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A&P II Ch. 17

QuestionAnswer
What does the endocrine system regulate? Growth, Development, Reproduction
2. What types of messengers does the endocrine system use? What other system is this similar to? Chemical messengers to relay info and instructions between cells// Like the nervous system
3. What are the four types of intercellular communication (discussed in the slides) and how are they different? Direct communication/ Exchange of ions and molecules btwn adjacent cells across gap junctions/ btwn two same type cells/ highly specialized and relatively rare/ used in heart
3. What are the four types of intercellular communication (discussed in the slides) and how are they different? Paracrine communication/ Uses chemical signals to transfer info from cell to cell within a SINGLE tissue/ Most common form of intercellular communication throughout the body
3. What are the four types of intercellular communication (discussed in the slides) and how are they different? Synaptic Communication/ Used by nervous system & limited to a very specific area/ occurs btwn neurons across synaptic clefts/ neurotransmitter when released at a synapse
3. What are the four types of intercellular communication (discussed in the slides) and how are they different? Endocrine Communication/ releases hormones into bloodstream/ Alters metabolic activities of many tissues and organs simultaneously
4. Which type of intercellular communication does the endocrine system employ? The nervous system? Hormones/ Neurotransmitters
5. What is a target cell in the endocrine system? Specific cells around the body that posses receptors needed to bind and interpret hormonal messages
6. What are three possible changes caused by hormones within target cells? Stimulate synthesis of enzymes or structural proteins/ Incr or decr rate of synth of products within the cell/ Turn a process within the cell up/down or on/off
7. Why do bound steroid hormones remain in circulation longer than free hormones? They are attached to carrier proteins
8. What is a hormone receptor? Protein molecule to which a particular hormone molecule binds strongly/ can respond to several diff hormones & diff tissues have diff combinations of receptors
9. The hormone receptors present on a cell determine what? Hormonal sensitivity
10. What are endocrine reflexes? How are they usually controlled? (negative feedback) Responds to changes inside and outside the body and directs long-term, body-wide activities/ Negative feedback mechanisms
11. What controls the endocrine system at the highest level? Hypothalamus
12. The hypothalamus works closely with what other structure? Pituitary gland
13. What are the three ways that the hypothalamus controls the endocrine system? Production of hormones (ADH, OT) released into bloodstream from the post lobe of pituitary gland/ Production of regulatory hormones controls activity of anterior lobe of pituitary gland/ Send sympathetic cmmds to adrenal medullae (E&NE)
14. What are the two classes of hypothalamic regulatory hormones and what are their functions? Releasing Hormones (RH)- Stimulates synth and secretion of hormones at anterior lobe
14. What are the two classes of hypothalamic regulatory hormones and what are their functions? Inhibiting Hormones (IH)- Prevents synth and secretion of hormones from the anterior lobe
15. How is the rate of secretion of hypothalamic regulatory hormones controlled? Negative feedback
16. Where is the thyroid? In the neck
17. What are thyroid follicles? Hollow spheres lined by cuboidal epithelium/ Secrete thyroid hormones
18. Which pituitary hormone stimulates production of thyroid hormones? Thyroid- Stimulating Hormone (TSH)
19. What does it mean that thyroid hormones have a calorigenic effect? Cells consume more energy resulting in incr heat generation/ has a strong, immediate, shot-lived increased cellular metabolism/ Affect most cells in body
20. Understand the T3/T4 homeostasis figure from slide 30. Know what normal conditions are (homeostasis), how they are disturbed, and each step that is taken to restore homeostasis.
21. Where are the parathyroid glands located? Embedded in posterior surface of thyroid gland
22. Understand the calcitonin homeostasis figure from slide 35. Know what homeostasis conditions are (don’t have
23. Understand the parathyroid hormone homeostasis figure from slide 36. Know what homeostasis conditions are (don’t have to know exact numbers), how they are disturbed, and each step that is taken to restore
homeostasis. Know the general effects of parathyroid hormone secretion.
24. Where are the adrenal glands located? Superior border of each kidney
25. What are the two subdivisions of the adrenal glands? Superficial adrenal cortex/ Inner adrenal medulla
26. What hormone is produced by the pineal gland and what are the functions of it? Melatonin/ influences circadian rhythms
27. Which are far more abundant, exocrine pancreatic cells or endocrine pancreatic cells? Exocrine pancreatic cells
28. What type of substance is produced by the exocrine pancreas? Produces alkaline, enzyme-rich fluid (digestive juice)
29. What type of cells (alpha or beta) produce insulin? Glucagon? Alpha produces glucagon/ Beta produces insulin
30. Understand the insulin homeostasis figure from slide 56. Know what homeostasis conditions are (don’t have to
31. Understand the glucagon homeostasis figure, slide 57. Know what homeostasis conditions are (don’t have to know exact numbers), how they are disturbed, and each step that is taken to restore homeostasis. Know the general effects of glucagon secretion.
32. What is hyperglycemia? Abnormally high glucose levels in the blood
33. What characterizes diabetes? By glucose concentrations high enough to overwhelm the reabsorption capabilities of the kidneys
34. What is the difference between type I and type 2 diabetes? Insulin dependent/ inadequate insulin production by pancreatic beta cells/ multi injections daily or continuous infusion/ 5%-10% of cases/ often develops in childhood
35. Why does untreated diabetes damage the kidneys? it overwhelms the filtration abilities of the kidneys b/c of excess glucose. This leads to poor blood quality
36. Understand each of the possible complications of untreated diabetes. Kidney degeneration, retinal damage, early heart attacks, peripheral nerve problems, peripheral nerve damage
37. What is DKA? Diabetic ketoacidosis: buildup of acids in blood when blood sugar remains too high for too long/ Vomiting, lethargy, coma, death
38. What is gestational diabetes? Can happen during pregnancy/ placenta produces hormones that counteract the effects of insulin/ it can be temporary
39. Which organs also have secondary endocrine functions? Intestines, kidneys, heart, thymus, gonads
40. Know the secondary endocrine functions from slides 69 – 73.
41. Which hormones decrease in concentration with aging? Growth & Reproductive hormones
42. Know all information from the handout “Hormone List” posted on Canvas and provided in class.
34. What is the difference between type I and type 2 diabetes? Non-insulin dependent/ most common form of diabetes/ tissues do not respond properly (insulin resistance)/ Associated with obesity
Created by: Clinton Perdue
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