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Human Anatomy 72616

Lecture 14-18

QuestionAnswer
Chapter 14: Nervous Tissue Central Nervous System (CNS) inclues: -Brain & Spinal Cord
Chp 14: Peripheral Nervous System (PNS) Includes: Crainal Nerves, Spinal Nerves, & Ganglia
Chp 14: Crainal Nerves has 12 pairs
Chp 14: Spinal Nerves has 31 pairs
Chp 14: Sensory & Motor Nervous System with both CNS & PNS components preform 3 general functions for receptors : - Collect information - Process & evaluates information - Initiate response
Chp 14: Collection Information Receptors goes through the PNS detects changes in enviroment ; passes information to the CNS. Detect stimuli (sensory input); Detects changes (dendrites of sensory neurons).
Chp 14: Process & evaluates information CNS determines required reponse. Motor neurons delivers impluses to effectors ( muscle glands)
Chp 14: Initiate response CNS initiates impluses (rapid movements of an electrical charge) that PNS carries to effectors (cells receiving the impluses, such as muscles or glands) to react to changes in evironment
Chp 14: Sensory Nervous System (afferent) recieves sensory information from receptor in PNS & transmits it to CNS of 2 subdividing components - Somatic sensory (conscious) - Visceral sensory unconscious of)
Chp 14: Somatic sensory (conscious) detection of stimuli through the general senses such as touch, pain, pressure, vibration, and proprioception
Chp 14: Visceral sensory unconscious of) impulses from blood vessels and viscera
Chp 14: sensory nervous system or afferent receives information from receptors
Chp 14: Somatic sensory (conscious) functions: general somatic senses (touch, pain, pressure, vibration, temperature, proprioception or position of joints & limbs
Chp 14: Somatic sensory (conscious) speacial senses: special senses (taste, vision, hearing, balance, & smell) with voluntary functions
Chp 14: Visceral sensory unconscious of) visceral receptors detect chemical composition of blood or stretch of organ wall (involuntary & not aware of them)
Chp 14: Motor nervous system (efferent) sends impulses from CNS through PNS to muscles and glands subdivided into two systems: -Somatic motor (somatic nervous system; SNS) -Autonomic motor (autonomic nervous system; ANS)
Chp 14: Somatic motor (somatic nervous system; SNS) voluntary; conducts impulses that cause contraction of skeletal muscles
Chp 14: Autonomic motor (autonomic nervous system; ANS) involuntary; conducts impulses that regulate smooth and cardiac muscle, as well as glands
Chp 14: CYTOLOGY of Nervous System • Two distinct types of cells within the nervous system -Neurons - Glial cells
Chp 14: Neurons The neuron is the basic structural unit of the nervous system • Conducts nerve impulses from one place to another
Chp 14: Neurons • Special characteristics: – High metabolic rate – Extreme longevity – Nonmitotic – Excitable (respond to a stimulus)
Chp 14: Glial cells nonexcitable cells that support and protect the neurons
Chp 14: Neuron Structure Neurons vary in shape, but most have a cell body, dendrites, and an axon
Chp 14: Cell body (soma) contains several organelles : – Nucleus with nucleolus – Mitochondria – Chromatophilic substances: free ribosomes and rough endoplasmic reticulum • Dendrites are short processes that branch from the cell body – Dendrites receive signals and transfer them to the cell body
Chp 14: Parts of a Neuron •Neuron •Cell body • Perikaryon • Neurotubules • Neurofilaments • Neurofibrils • Dendrites • Axon/nerve fiber • Axon hillock • Axon collaterals • Terminal arborizations or telodendria • Synaptic Knob
Chp 14: Neuron Structural & functional cell of the nervous system; sometime called a nerve cell
Chp 14: Cell body Nucleus & surrounding cytoplasm of a neuron (excluding its dendrites & axon )
Chp 14: Perikaryon Most often refers to the cytoplasm within the cell bodySometime used to describe the entire body.
Chp 14: Neurotubules Microtubles that form the cytoskeleton
Chp 14: Neurofilaments intermediate filaments that aggregate to form bundles called neurofibrils
Chp 14: Neurofibrils Aggregates of neurofilaments that extend as a complexnetwork into dendrites and axons, their tensilstrength provides support for these processes
Chp 14: Dendrites Neuron processes that conducts information to the cell body (input)
Chp 14: Axon/nerve fiber Neuron process that conducts nerve impluses away from the cell cell body (output)
Chp 14: Axon hillock Triangular region connecting cell body to axon
Chp 14: Axon collaterals Side branches of an axon
Chp 14: Terminal arborizations or telodendria Fine terminal branches of an axon or axon collateral
Chp 14: Synaptic Knob Slightly expanded regions at the tips of terminal arborizations
Chp 14: Axon An axon transmits nerve impulses away from the cell body and toward other cells
Chp 14: Neurons without axon Neurons without an axon are called anaxonic
Chp 14: Unipolar single dendrite, short process branches like a T from cell body start out as bipolar then the 2 processes fuse into a single process • -most sensory neurons of the PNS are unipolar neurons
Chp 14: Bipolar two dendrite processes, one dendrite and one axon • -bipolar (one axon & one dendrite) is uncommon in humans; only in olfactory epithelium of nose & retina of eye
Chp 14: Multipolar many dendrites and a single axon; most common type of neuron • -multipolar is most common – motor neurons to muscles & glands
Chp 14: Functional classes of neurons: 3 types according to the direction the nerve impulse travels relative to the CNS: -Sensory neurons (afferent) – Motor neurons (efferent) – Interneurons (association neurons)
Chp 14: Sensory neurons (afferent) transmit impulses about stimuli from sensory receptors to CNS
Chp 14: Motor neurons (efferent) transmit impulses from CNS to muscles or glands
Chp 14: Interneurons (association neurons) retrieve, process, and store information; communicate between sensory and motor neurons
Chp 14: Glial cells (neuroglia) • Found in both CNS and PNS • Smaller and more numerous than neurons • Capable of mitosis • Typically do not transmit impulses but do help with the functions of neurons • -guide young neurons to their destination during development • -support, protec
Chp 14: Glial cells (neuroglia) contains: contains 86 billion neurons, same with neuroglia (currently 50% neuroglia, 50% neurons)
Chp 14: Four types of glial cells in CNS – Astrocytes – Ependymal cells – Microglial cells – Oligodendrocytes
Chp 14: Astrocytes Most abundant glial cells in the CNS; functions include: – Help form the blood–brain barrier (BBB) – Regulate tissue fluid composition – Form a structural network – Replace damaged neurons – Assist neuronal development – Help regulate synaptic transmission – Change synapse numbers
Chp 14: Astrocytes Most abundant glial cells in the CNS; functions include part 2 : -oversee up to 2 million synapses -undergo astrocytosis (replacement of damaged neurons) -assist neuronal development by secreting chemicals -star-like shape -touch capillaries & neurons -most abundant glial cells in CNS -90% of nervous tissue in so
Chp 14: Ependymal Cells Ciliated cuboidal epithelial cells that line ventricles of brain and central canal of spinal cord • Help produce cerebral spinal fluid (CSF) and help form choroid plexus -ependymal cells + nearby capillaries form the choroid plexus -cilia help circul
Chp 14: Microglial Cells Microglia are small cells that move through CNS and engulf debris -5% in CNS -wander in CNS -replicate in response to infection -phagocytic like macrophages
Chp 14: Oligodendrocytes • Associated with CNS axons only • Wrap themselves around the axons like electrical tape wrapped around a wire • Produce myelin, which is an insulator of electrical activity
Chp 14: Two types of glial cells are found in the PNS:
Chp 14: Satellite Cells physically separate cell bodies in a ganglion from interstitial fluid -regulate continuous exchange of nutrients & waste products between neurons & environment
Chp 14: Neurolemmocytes (Schwann cells) elongated, flattened cells, produce myelin sheath around nerve fibers in the PNS
Chp 14: Myelination of Axons Myelin affects the ability of neurons to conduct nerve impulses (action potentials)
Chp 14: Myelination the process of wrapping the axon with a myelin sheath to electrically insulate it
Chp 14: Unmyelinated Axons Unmyelinated axons propagate impulses by continuous conduction, where the impulse travels along the entire length of the axon membrane
Chp 14: Nerves nerve is a cablelike bundle of parallel axons
Chp 14: Three types of connective tissue wrappings are in and around nerves –Endoneurium: – Perineurium: – Epineurium:
Chp 14: Endoneurium: around each individual axon
Chp 14: Perineurium: around each fascicle of axons
Chp 14: Epineurium around the entire nerve
Chp 14: Synapses Synapses are specialized junctions between two neurons, or between a neuron and a muscle or gland cell
Chp 14: A typical synapse consists of –Presynaptic neuron: – Synaptic cleft: – Postsynaptic neurons
Chp 14: Presynaptic neuron has synaptic knobs at axon endings for sending signal
Chp 14: Synaptic cleft narrow space between cells
Chp 14: Postsynaptic neuron Recives signals
Chp 14: hree common types of synapses, named based on which part of the postsynaptic neuron is contacted - Axodendrictic - Axosomatic - Axoaxonic
Chp 14: Axodendrictic Axodendrictic- between synaptic knobs of axon and dendrites
Chp 14: Axosomatic Axosomatic- between synaptic knobs of axon and soma
Chp 14: Axoaxonic Axoaxonic - between synaptic knobs of one axon and axon
Chp 14: Electrical synapses Electric synapes involve gap junctions between joined cells – Ions rapidly flow from one cell to another – Rare in the nervous system
Chp 14: Chemical synapses Chemical synapses involve release of neurotransmitter by presynaptic cell upon arrival of impulse at end of axon
Chp 14: Neurons are grouped into patterns called neural circuits
Chp 14: Converging: impulses come together to a single postsynaptic neuron
Chp 14: Example of Converging: saliva production . food pictures, smell of food, looking at clock for dinner, hearing food preparation lead to a single output, which is salivation
Chp 14: Diverging mpulses spread from one presynaptic neuron to many postsynaptic neurons
Chp 14: Example of Diverging a few neurons in the motor cortex of brain stimulating thousands of muscle fibers in a muscle
Chp 14: Reverberating: cyclical stimulation of the breathing circuit
Chp 14: Example of Reverberating: breathing rhythm
Chp 14: Parallel-after-discharge: several neurons process the information simultaneously (in parallel)
Chp 14: Example of Parallel-after-discharge: higher-order thinking (mathmatic equations and calcualtions )
Chp 14: Nervous tissue derived from the ectoderm germ layer
Chp 14: Neural plate: thickened ectoderm that undergoes neurulation
Chp 14: Neural groove develops in plate; cells at margin become neural crest
Chp 14: Neural crest Folds on either side of groove grow together forming hollow neural tube
Chp 14: Neural tube forms the central nervous system
Chp 14: Neurulation formation of nervous tissue structures
Chapter 15: Active synapses intelligence is determined by the number of active synapses among neurons
Chp 15: Human size brain: increased in volume & weight until limited by skull size; the folds on surface increased, so more neurons can fit -very versatile response to various stimuli simultaneously (more than a computer)
Chp 15: The brain is composed of 4 major regions: – Cerebrum – Diencephalon – Brainstem – Cerebellum
Chp 15: Structures of the Cerebrum -folds or gyri -sulci or shallow depressions between folds
Chp 15: brain is associated with 12 pairs of cranial nerves Outer surface of brain’s cerebrum is wrinkled
Chp 15: Gyri: folds
Chp 15: Sulci: depressions between folds
Chp 15: Directional terms used include -Anterior (rostal) -Posterior (caudal)
Chp 15: Anterior (rostal) towards the nose
Chp 15: Anterior (rostal) towards the tail
Chp 15: telencephalon envelops diencephalon
Chp 15: formation of sulci & gyri (develop at late fetal period)
Chp 15: three brain vesicles develop -> give rise to regions of brain 1. forebrain or prosencephalon 2. midbrain or mesencephalon 3. hindbrain or rhombencephalon
Chp 15: Prosencephalon develops into telencephalon (develops into cerebrum)
Chp 15: Diencephalon developes into epithalamus, thalamus, hypothalamus
Chp 15: Mesencephalon develops into midbrain (develops into cerebral peduncle, superior & inferior colliculi)
Chp 15: Rhombencephalon develops into the 4th ventricle
Chp 15: Metencephalon developes into pons and cerebellum
Chp 15: Myelencephalon developes into medulla oblongata
Chp 15: 2 distinct tissue matter areas in brain & spinal cord: : gray matter & white matter
Chp 15: Gray matter: – Houses motor neuron and interneuron cell bodies, dendrites, telodendria, unmyelinated axons – Forms cerebral cortex, which covers surface of most of adult brain
Chp 15: Within the white matter, gray matter forms deep clusters of neuron cell bodies called cerebral nuclei
Chp 15: White matter: Made up of myelinated axons – Deep to the gray matter of the cortex
Chp 15: Cranial meninges Pia Mater made up of made up of areolar connective tissue (adheres to the brain
Chp 15: Arachnoid mater made up of made up of collagen & elastic fibers (form a delicate web called arachnoid trabeculae)
Chp 15: Subarachnoid space deep into the arachnoid mater where arachnoid trabeculae extend -between arachnoid mater & dura mater is a potential space (subdural space)
Chp 15: potential space becomes an actual space when fluids & blood accumulate called Subdural hematoma
Chp 15: Cranial meninges are connective tissues that function in: – Separating brain from bones of cranium – Protecting blood vessels of brain; form some large veins that drain blood from brain – Containing and circulating cerebrospinal fluid
Chp 15: Three layers of cranial meninges • Pia mater: thin, innermost layer adhering to brain • Arachnoid mater • Dura mater
Chp 15: Pia mater- thin, innermost layer adhering to brain
Chp 15: Arachnoid mater- has web of fibers called arachnoid trabeculae
Chp 15: Dura mater- tough outer layer
Chp 15: Dura mater: tough outer layer with two sublayers -meningeal layer - periosteal layer
Chp 15: meningeal layer Deeper meningeal layer (superficial to subdural space)
Chp 15: periosteal layer More superficial periosteal layer
Chp 15: Dura mater is made up of dura mater is made up of dense irregular connective tissue
Chp 15: Periosteal layer of dura mater forms forms the periosteum on internal surface of cranial bones
Chp 15: Epidural space -potential space between dura mater & skull bone; contains arteries, veins that nourish meninges & cranial bones
Chp 15: The meningeal layer extends into cranial cavity at four locations to form double-layered dura cranial dural septa
Chp 15: four locations to form double-layered dura called cranial dural septa – Falx cerebri – Tentorium cerebelli – Falx cerebelli – Diaphragma sellae
Chp 15: Falx cerebri- projects into longitudinal fissure; separates left and right cerebral hemispheres
Chp 15: Tentorium cerebelli- horizontal fold that separates cerebrum from cerebellum
Chp 15: Falx cerebelli- separates left and right cerebellar hemispheres
Chp 15: Diaphragma sellae- small septum between pituitary and hypothalamus
Chp 15: Dural venous sinuses location- form in locations where the two layers of the dura mater have separated : -Superior sagittal sinus -Inferior sagittal sinus
Chp 15: Superior sagittal sinus- located within the superior margin of the falx cerebri
Chp 15: Inferior sagittal sinus- located within the inferior margin of the falx cerebri
Chp 15: Transverse sinuses- located within the posterior border of the tentorium cerebelli
Chp 15: Occipital sinus- located in the posterior vertical border of the falx cerebelli
Chp 15: dural venous sinuses formation- are formed from separation of meningeal & periosteal layers in specific areas that is filled with blood (triangular in X-section, but veins without valves to regulate blood flow)
Chp 15: dural venous sinuses "veins'- large veins that drain blood from brain to internal jugular veins
Chp 15: cranial dural septa 4"location"- double layer of dura mater as flat partitions into cranial cavity at 4 locations separates specific parts of brain; provide additional stability & support to the brain 1. falx cerebri 2. entorium cerebelli: 3.f alx cerebelli 4. diaphragma sellae
Chp 15: 1. falx cerebri "location"- ocated in midsagittal plane; largest dural septa; projects between left & right cerebral hemisphere (longitudinal fissure); attaches anteriorly to crist galli of ethmoid; posteriorly to internal occipital crest of skull
Chp 15: 2. tentorium cerebelli "location"- orizontal fold of dura mater; separates occipital & temporal lobes of cerebrum from cerebellum; tentorial notch is a gap at anterior surface for passage of brainstem
Chp 15: 3. falx cerebelli "location"- vertical partition separates right & left cerebellar hemispheres
Chp 15: 4. diaphragma sellae "location"- smallest of dural septa; forms roof over sella turcica of sphenoid bone; infundibulum (stalk) passes a small opening in diaphragma sellae (attaches pituitary gland to base of hypothalamus
Chp 15: Brain Ventricles- from lumen of embryonic neural tube -cavities within the brain -continuous with the central canal of spinal cord
Chp 15: Cerebrospinal fluid (CSF): clear liquid that circulates in ventricles and subarachnoid space
Chp 15: Cerebrospinal fluid (CSF) "functions"- – Buoyancy – Protection: –Environmental stability choroid plexus –ependymal cells
Chp 15: – Buoyancy: brain “floats” in the CSF
Chp 15: – Protection: provides liquid cushion
Chp 15: –Environmental stability transports nutrients and removes waste from brain • Formed by the choroid plexus in each ventricle
Chp 15: ependymal cells Composed of a layer of ependymal cells and the capillaries that lie within the pia mater
Chp 15: CSF does- supports 95% of the brain’s weight • -protects nervous tissue from chemical fluctuations • -excess CSF transported to venous circulation -> filtered from the blood -> secreted in urine in urinary system
Chp 15: (BBB) Blood Brain Barrier- Blood–brain barrier (BBB) regulates what substances can enter interstitial fluid of brain
Chp 15: BBB is missing or reduced in three locations of CNS – Choroid plexus (because the capillaries must be permeable to make CSF) – Hypothalamus (hormones are made that need ready access to blood) – Pineal gland (hormones are made that need ready access to blood)
Chp 15: Cerebrum oluntary motor, visual, auditory activities -intelligence, reasoning, sensory perception, thought, memory, judgment
Chp 15: Cerebrum "location"- Cerebrum is location of conscious thought and origin of intellectual functions
Chp 15: Cerebrum contains: Contains an outer cortex, inner white matter, and deep regions of gray matter called cerebral nuclei - Surface is marked by gyri (ridges), sulci (grooves), and deep fissures
Chp 15: Cerebrum composed- The cerebrum is composed of two halves called left and right cerebral hemispheres
Chp 15: longitudinal fissure Hemispheres are divided by a longitudinal fissure that extends along the midsagittal plane
Chp 15: corpus callosum The corpus callosum is the largest tract that connects the two hemispheres
Chp 15: Each hemisphere is divided into five lobes 1. Frontal lobe 2. Parietal lobe 3. Temporal lobe 4. Occipital lobe 5. Insula
Chp 15: Frontal lobe Frontal lobe is located deep to the frontal bone and forms anterior part of cerebral hemisphere
Chp 15: central sulcus & lateral sulcus Ends posteriorly at central sulcus; inferior border marked by lateral sulcus
Chp 15: Frontal lobe function voluntary movement, concentration, verbal communication, decision making, planning, and personality
Chp 15: Parietal lobe forms superoposterior part of each hemisphere and is under parietal bone
Chp 15: Precentral gyrus s ridge in frontal lobe just anterior to central sulcus
Chp 15: parieto-occipital sulcus Terminates anteriorly at the central sulcus, laterally at the lateral sulcus, and posteriorly
Chp 15: Postcentral gyrus is ridge in parietal lobe immediately posterior to central sulcus
Chp 15: Parital lobe function Parietal lobe is involved with general sensory functions
Chp 15: Temporal lobe Temporal lobe is inferior to lateral sulcus, under the temporal bone
Chp 15: Temporal lobe function temporal lobe Involved with hearing and smell
Chp 15: Occipital lobe Occipital lobe is in posterior region of each hemisphere underneath occipital bone
Chp 15: Occipital lobe function Processes incoming visual information and stores visual memories
Chp 15: Insula Insula is deep to the lateral sulcus
Chp 15: Insula function Involved in interoceptive awareness, emotion, empathy, taste
Chp 15: Three categories of functional areas are recognized: – Motor areas: control voluntary motor functions – Sensory areas: provide conscious awareness of sensation – Association areas: integrate and store information
Chp 15: Primary motor cortex (somatic motor area) controls Primary motor cortex (somatic motor area) controls
Chp 15: Primary motor cortex (somatic motor area) location Located within precentral gyrus; axons project contralaterally to brainstem and spinal cord
Chp 15: Primary motor cortex (somatic motor area) innervation Innervation to various body parts can be diagrammed as a motor homunculus on the precentral gyrus
Chp 15: Primary motor cortex (somatic motor area) indication indicates the amount of motor control that area receives
Chp 15: Motor speech area (Broca area) controls controls muscular movements necessary for vocalization
Chp 15: Motor speech area (Broca area) location Located in most individuals within the inferolateral portion of the left frontal lobe
Chp 15: Frontal eye field controls helps control and regulate eye movements
Chp 15: Frontal eye field location Located on superior surface of middle frontal gyrus, immediately anterior to premotor cortex -anterior to premotor cortex in frontal lobe (control & regulate eye movements)
Chp 15: Primary Somatosensory Cortex indication indicates the amount of sensory information received by that region
Chp 15: Primary Somatosensory Cortex location is located within the postcentral gyrus – This area receives general somatic sensory information from touch, pressure, pain, and temperature receptors
Chp 15: Sensory homunculus may be traced on surface
Chp 15: Primary visual cortex processes visual information; located in occipital lobe
Chp 15: Primary auditory cortex processes auditory information; located in temporal lobe
Chp 15: Primary gustatory cortex processes taste information; located in insula
Chp 15: Primary olfactory cortex provides awareness of smell; located in temporal lobe
Chp 15: primary motor & primary sensory cortical regions primary motor & primary sensory cortical regions are connected to adjacent association areas
Chp 15: primary motor & primary sensory cortical regions intergrates integrate new sensory inputs with memories of past experience
Chp 15: premotor cortex located Located in frontal lobe just anterior to precentral gyrus
Chp 15: somatosensory association areas somatosensory association areas store sensory/sensation memories
Chp 15: visual association area intergrates integrates a visual information into a recognizable picture of an object, face, etc
Chp 15: association areas association areas must work together with motor speech area
Chp 15: Premotor cortex coordinates skilled motor activities
Chp 15: Somatosensory association area integrates integrates and interprets sensory information
Chp 15: Somatosensory association area location Located in parietal lobe just posterior to post central gyrus
Chp 15: Auditory association area interpretation interprets characteristics of sound and stores memories of sound
Chp 15: Auditory association location Located in temporal lobe, posteroinferior to primary auditory cortex
Chp 15: Visual association area function processes visual information
Chp 15: Visual association area location Located in occipital lobe, surrounding primary visual cortex
Chp 15: Wernicke area recognition recognizes and comprehends spoken and written language
Chp 15: Wernicke area location located in left hemisphere overlapping the parietal and temporal lobes
Chp 15: Higher-Order Processing Centers association association areas are considered higher order
Chp 15: Higher-Order Processing Centers function unctions such as speech, cognition, understanding spatial relationships, and general interpretation
Chp 15: Central White Matter Tracts • Brain’s white matter is deep to cortical gray matter • Composed primarily of myelinated axons
Chp 15: Most axons are bundled into tracts of three types: - Association tracts -Commisural tracts -Projection tracts
Chp 15: - Association tracts Association tracts connect areas within one hemisphere
Chp 15: -Commisural tracts Commissural tracts connect two hemispheres
Chp 15: -Projection tracts Projection tracts connect cerebrum to lower areas (e.g., spinal cord)
Chp 15: Arcuate fibers Arcuate fibers within a lobe
Chp 15: Longitudinal fasciculi Longitudinal fasciculi connect different lobes of same hemisphere
Chp 15: association tracts -assocation tracts connect different regions of cerebral cortex with in same hemisphere
Chp 15: arcuate fibers -association tracts connect different regions of cerebral cortex with in same hemisphere
Chp 15: longitudinal fasciculi longitudinal fasciculi are long tracts, connect gyri in different lobes of same hemisphere (example: Wernicke area & motor speech area connection)
Chp 15: commissural tracts: commissural tracts: link left & right cerebral hemisphere (example: corpus callosum: C-shaped smaller anterior & posterior commissures
Chp 15: projection tracts: projection tracts: link cerebral cortex to inferior brain regions & spinal cord (example: corticospinal tracts between cerebrum & brainstem & spinal cord for motor signals
Chp 15: -internal capsule: tracts between cerebral nuclei
Chp 15: Cerebral nuclei (basal nuclei) Cerebral nuclei (basal nuclei) are masses of gray matter located deep within brain’s white matter
Chp 15: Caudate nucleus- helps coordinate walking - C-shaped; to stimulate appropriate muscles for pattern & rhythm of arm, & leg movements when walking
Chp 15: Amygdaloid body- participates in emotional expression -posterior to caudate nucleus for emotion expression, control of behavioral activities, mood development
Chp 15: Lentiform nucleus- involved in movement and muscle tone - made up of putamen & globus pallidus between insula & diencephalon for muscular movement (subconscious), regulate skeletal muscle tone
Chp 15: Cerbral nuceli(basal nuclei) Composed of putamen and globus pallidus
Chp 15: Claustrum- consciousness and processing of multiple sensory stimul -nternal to insula (unclear function, but with extensive connection with cerebral cortex areas so maybe consciousness & integrating info from multiple senses
Chp 15: corpus striatum- term of the striped appearance of internal capsule
Chp 15: Diencephalon- conscious awareness of emotional states
Chp 15: Components of the diencephalon include: – Epithalamus – Thalamus – Hypothalamus
Chp 15: Epithalamus- The epithalamus partially forms posterior roof of diencephalon and covers third ventricle
Chp 15: Components of the Epithalamus – Pineal gland: – Habenular nuclei:
Chp 15: – Pineal gland: Pineal gland: secretes melatonin, a hormone that regulates circadian rhythm
Chp 15: – Habenular nuclei: Habenular nuclei: relays signals from limbic system to midbrain; involved in visceral and emotional responses to odor
Chp 15: Thalamus filter so only few sensory info is forwarded to the cerebrum
Chp 15: interthalamic nuclei connects the right & left thalamus
Chp 15: Function of interthalamic nuceli anterior group motor cortex excitability & mood
Chp 15: lateral group sensory & emotional info
Chp 15: medial group sensory & emotional info
Chp 15: posterior group visual info, auditory, sensory info
Chp 15: anterior nucleus thirst center
Chp 15: arcuate nucleus appetite, gonadotropin-releasing hormone, growth hormone releasing hormone, prolactin inhibiting hormone
Chp 15: mamillary body controls swallowing, olfaction sensation processing
Chp 15: paraventricular nucleus oxytocin production
Chp 15: preoptic area thermostat nfluences heart rate, blood pressure, digestive activities, respiration -secretes hormones to influence pituitary gland
Chp 15: suprachiasmatic nucleus controls sleep-wake cycle
Chp 15: supraoptic nucleus antidiuretic hormone production
Chp 15: ventromedial nucleus satiety
Chp 15: Hypothalamus is the anteroinferior region of diencephalon • Thin, stalklike infundibulum extends inferiorly from hypothalamus to attach to pituitary gland • Specific nuclei control various functions in body: – Master control of the autonomic nervous system – Mast
Chp 15: Brainstem connects forebrain and cerebellum to spinal cord Passageway for all tracts between cerebrum and spinal cord
Chp 15: Brainstem contains: Contains many autonomic and reflex centers required for survival • Houses nuclei of many of the cranial nerves
Chp 15: Three regions form the brainstem: – Midbrain – Pons – Medulla oblongata
Chp 15: Midbrain Midbrain is superior portion of brainstem
Chp 15: Midbrain has nuceli 2 cranial nerves for eye movement: CN III oculomotor nerve & trochlear nerve (CNIV)
Chp 15: Cerebral aqueduct extends through midbrain and connects third and fourth ventricles
Chp 15: Cerebral aqueduct surrounded by Surrounded by periaqueductal gray matter
Chp 15: tegmentum integrates tegmentum integrates info from cerebrum & cerebellum & responsible for involuntary motor command to erector spinae muscles of the back to maintain posture while standing, etc.
Chp 15: Tegmentum is between substantia nigra and periaqueductal gray; relays information between cerebrum and cerebellum
Chp 15: substantia nigra melanin pigmented 2 nuclei; neurons produce neurotransmitters dopamine for movement control, emotional response, & pleasure and pain
Chp 15: substantia nigra Degeneration of substantia nigra underlies Parkinson’s disease
Chp 15: Somatic motor axon Somatic motor axons descend from primary motor cortex through cerebral peduncles to spinal cord
Chp 15: Superior cerebellar peduncles connect cerebellum to midbrain
Chp 15: -tectum: in midbrain; with 2 nuclei called tectal plate
Chp 15: -superior colliculi: visual reflex center
Chp 15: inferior colliculi: auditory reflex center
Chp 15: Pons Pons bulging region on anterior brainstem
Chp 15: pons with sensory & motor tracts connect connect to brain & spinal cord
Chp 15: superior olivary complex: auditory input & pathway of sound localization
Chp 15: Middle cerebellar peduncles are transverse fibers that connect pons to cerebellum
Chp 15: Middle cerebellar peduncles contains Contains autonomic nuclei in pontine respiratory center that help regulate breathing
Chp 15: Houses sensory and motor cranial nerve nuclei for trigeminal for trigeminal (CN V), abducens (CN VI), and facial (CN VII) nerves
Chp 15: Superior olivary complex nuclei receive Superior olivary complex nuclei receive auditory input and help localize sound source
Chp 15: Medulla oblongata (medulla) is most inferior part of brainstem
Chp 15: Pyramids are composed of motor projection tracts called the corticospinal tracts
Chp 15: Most axons in pyramids cross midline at decussation of the pyramids
Chp 15: decussation of the pyramids Contains nucleus cuneatus and nucleus gracilis which relay somatic sensory information to thalamus
Chp 15: Medulla oblongata (medulla) contains Contains several autonomic nuclei
Chp 15: Cardiac center: regulates heart rate and its strength of contraction
Chp 15: Vasomotor center: controls blood pressure by regulating contraction and relaxation of smooth muscle in walls of arterioles
Chp 15: Medullary respiratory center: regulates respiratory rate - involved in coughing, sneezing, salivation, swallowing, gagging, and vomiting
Chp 15: Cerebellum 2 hemispheres; each hemisphere has 2 lobes (anterior & posterior) separates by primary fissure
Chp 15: vermis separates left & right cerebellar hemispheres
Chp 15: Cerebellum now believed to be responsible for responsible for mood, behavior, cognition, language
Chp 15: The cerebellum is the The cerebellum is the second largest part of brain
Chp 15: The cerebellum partitioned into three regions -cerebellar cortex -arbor vitae -Cerebellar nuclei
Chp 15: Outer gray matter layer of cerebellar cortex
Chp 15: Internal region of white matter, called the arbor vitae
Chp 15: In deepest layer Cerebellar nuclei
Chp 15: Folds of cerebellar cortex are called Folia
Chp 15: Cerebellar Peduncles • Three thick tracts link the cerebellum with the brainstem: – Superior cerebellar peduncles: connect midbrain to cerebellum – Middle cerebellar peduncles: connect pons to cerebellum Brain & Cranial Nerves Notes 13 – Inferior cerebellar peduncles: connect medulla oblongata to cerebellum
Chp 15: Limbic System is composed of cerebral and diencephalic structures that form a ring around the diencephalon
Chp 15: Limbic System structure Its structures process and experience emotions
Chp 15: Limbic System affect Affects memory formation through integration of past memories of physical sensations with emotional states
Chp 15: Cingulate gyrus: ridge superior to corpus callosum; brings emotions into consciousness
Chp 15: Parahippocampal gyrus: tissue associated with hippocampus (functions in memory)
Chp 15: Hippocampus: nucleus shaped like a seahorse; essential in consolidating long-term memories
Chp 15: Amygdaloid body: involved nvolved in emotion, especially fear; helps sort and code memories based on how they are emotionally perceived
Chp 15: Olfactory bulbs, olfactory tract, olfactory cortex: odors can provoke emotions/memories
Chp 15: Fornix: thin tract of white matter connecting hippocampus with other limbic structures
Chp 15: Various nuclei in diencephalon also contribute contribute to emotional function
Chp 15: abbrevrated for "S" Sensory
Chp 15: abbrevrated for "M" Motor
Chp 15: abbrevrated for "B" Both Sensory & Motor
Chp 15: Functions S --- CN I Olfactory --->
Chp 15: S ---> CN II Optic --> Optic canal
Chp 15: M ---> CN III Ocolumotor
Chp 15: M ---> CN IV Trochlear ---> Superior Orbital Fissure
Chp 15: B ---> CN V Trigeminal ---> Superior Orbital Fissure
Chp 15: M---> CN VI Abudens ---> Superior Orbital Fissure
Chp 15: B---> CN VII Facial
Chp 15: S-->CN VIII Vestibulocochlear ---> Internal Acoustic Meatus
Chp 15: B ---> CN IX Glossophryngeal ---> Jugular Foremen
Chp 15: B ---> X Vagus ---> Jugular Foremen
Chp 15: M---> XI Accessory ---> Jugular Foremen
Chp 15: M---> XII Hypoglossal ---> Hypoglossal canal
Chp 15: V1 Ophthalmic Branch (goes through Superior Orbital Fissure)
Chp 15: V2 Maxillary Branch (foreman Rotundum)
Chp 15: V3 Mandibular Branch (Foreman Ovale)
Chapter 16: Spinal cord Spinal cord is a vital link between brain and rest of the body
Chp 16: Spinal nerves serve two important functions: • A pathway for sensory and motor impulses • Responsible for reflexes—our quickest reactions to stimuli
Chp 16: Spinal cord is is ¾ of an inch in diameter, 16–18 in. long
Chp 16: Spinal cord extends Extends from foramen magnum to L1 vertebra
Chp 16: Five parts of spinal cord named for the nerves that attach to them (listed superior to inferior) • Cervical part • Thoracic part • Lumbar part • Sacral part • Coccygeal part
Chp 16: conus medullaris The tapering inferior end of spinal cord
Chp 16: Cauda equina: Cauda equina: “Horse’s tail”—axons that extend inferiorly from spinal cord’s conus medullaris
Chp 16: Filum terminale: Filum terminale: Thin strand of pia mater within cauda equina that attaches conus medullaris to coccyx
Chp 16: cervical enlargement The cervical enlargement is located in the inferior cervical part of the spinal cord and innervates the upper limbs
Chp 16: lumbosacral enlargement The lumbosacral enlargement extends through the lumbar and sacral parts of the spinal cord and innervates the lower limbs
Chp 16: External surface of cord has two longitudinal depressions • Anterior median fissure Posterior median sulcus
Chp 16: How many nerves in the cervical nerves 8 cervical nerves (C1–C8
Chp 16: How many nerves in the thoracic nerves 12 thoracic nerves (T1–T12
Chp 16: How many nerves in the lumbar nerves 5 lumbar nerves (L1–L5)
Chp 16: How many nerves in the sacral nerves 5 sacral nerves (S1–S5)
Chp 16: How many nerves in the coxccyegeal nerves 1 coccygeal nerve (Co1
Chp 16: Spinal Nerves spinal nerves are mixed nerves that contain both motor and sensory axons
Chp 16: dura mater only only has meningeal layer, NO periosteal layer
Chp 16: pia mater is made up of is made up of elastic and collagen fibers
Chp 16: Spinal cord meninges are continuous with cranial meninges
Chp 16: Epidural space sits between dura and periosteum of vertebra
Chp 16: subdural space potential space separating dura mater from deeper arachnoid mater
Chp 16: Subarachnoid space is a real space filled with cerebrospinal fluid (CSF
Chp 16: innermost meninx that adheres directly to the spinal cord pia mater
Chp 16: Pia mater consist of Consists of a delicate layer of elastic and collagen fibers
Chp 16: Has paired, lateral triangular extensions called denticulate ligaments
Chp 16: Gray matter: dendrites and cell bodies of neurons, unmyelinated axons, and glial cells
Chp 16: White matter: Myelinated axons
Chp 16: Gray matter is centrally located in spinal cord Subdivided into • Anterior horns • Lateral horns • Posterior horns • Gray commissure
Chp 16: Within gray matter are functional groups of neuron cell bodies called nuclei
Chp 16: Sensory nuclei in posterior horns contain interneuron cell bodies of somatic sensory nuclei and visceral sensory nuclei
Chp 16: Motor nuclei in the anterior horns contain somatic motor nuclei
Chp 16: Autonomic motor nuclei are in the lateral horns
Chp 16: Anterior horns house somas of somatic motor neurons
Chp 16: Lateral horns contain somas of autonomic motor neurons
Chp 16: Posterior horns contain axons of sensory neurons and cell bodies of interneurons
Chp 16: Gray commissure contains unmyelinated axons for communication between right and left side
Chp 16: The gray commissure houses a narrow Central canal
Chp 16: Lateral horns only found -Only found in the T1–L2 parts of spinal cord
Chp 16: Partitioned into three regions, each called a funiculus: • Posterior funiculus • Lateral funiculus • Anterior funiculus
Chp 16: Anterior funinculi Anterior funinculi connected by white commissure
Chp 16: Axons within each funiculus are organized into smaller structural units called tracts
Chp 16: anterior and lateral funiculi contain ontain both ascending and descending tracts (sensory and motor axons, respectively)
Chp 16: posterior funiculus contains contains only sensory (ascending) tracts
Chp 16: 31 pairs of spinal nerves extend from spinal cord • Made up of motor and sensory axons • Contain connective tissue wrappings: • Endoneurium • Perineurium • Epineurium
Chp 16: Multiple anterior rootlets arise from the spinal cord and merge to form a single anterior root
Chp 16: Anterior roots contain motor axons only
Chp 16: Multiple posterior rootlets derive from a single posterior root
Chp 16: Posterior roots contain sensory axons only
Chp 16: Motor axons arise from cell bodies in the anterior and lateral horns of the spinal cord
Chp 16: Sensory axons arise from cell bodies in the posterior root ganglion, which is attached to the posterior root
Chp 16: Each anterior root and its corresponding posterior root unite within the intervertebral foramen to become a Spinal nerve
Chp 16: Spinal nerves contain contains both motor & sensory axons
Chp 16: posterior ramus The posterior ramus innervates the deep muscles and skin of the back
Chp 16: anterior ramus The anterior ramus innervates the anterior and lateral portions of the trunk and the upper and lower limbs
Chp 16: multiple anterior rootlets and multiple posterior rootlets arises from the spinal cord
Chp 16: dermatome A dermatome is a segment of skin supplied by a single spinal nerve
Chp 16: Anesthesia in a region could indicate specific spinal nerve damage
Chp 16: Shingles rash includes blisters along dermatome
Chp 16: referred visceral pain pain in one organ is mistakenly referred to a dermatome (potentially nowhere near the organ in pain)
Chp 16: Cervical Plexuses Left and right cervical plexuses are formed by anterior rami of spinal nerves C1–C4
Chp 16: phrenic nerve The phrenic nerve originated primarily from C4 and some contributing axons of C3 and C5
Chp 16: phrenic nerve functions Travels through the thoracic cavity to innervate the diaphragm
Chp 16: brachial plexuses he left and right brachial plexuses are networks of nerves that supply the upper limbs
Chp 16: brachial plexus has 2 divisions anterior division innervates muscles that flex the upper limbs; posterior division innervates muscles that extend the upper limbs
Chp 16: Anterior rami of C5–T1 form the roots unite to form the: Superior trunk • Middle trunk • Inferior trunk
Chp 16: Superior trunk: Nerves C5 & C6
Chp 16: Middle trunk: Nerves C7
Chp 16: Inferior trunk Nerves C8 & T1
Chp 16: The anterior and posterior divisions converge to form three cords: • Posterior cord • Medial cord • Lateral cord
Chp 16: Five major terminal branches emerge from the three cords • Axillary nerve • Median nerve • Musculocutaneous nerve • Radial nerve • Ulnar nerve
Chp 16: Nerve plexus A nerve plexus is a network of interweaving anterior rami of spinal nerves
Chp 16: Anterior rami of spinal nerves T1–T11 are intercostal nerves
Chp 16: intercostal nerves travel in the spaces between adjacent ribs
Chp 16: Spinal nerve T12 is called a subcostal nerves
Chp 16: subcostal nerves arises below the ribs
Chp 16: T1 the intercostal nerves do not form plexuses • Part of T1 helps form brachial plexus; part of T1 lies in first intercostal space
Chp 16: T2 nnervates intercostal muscles of the second intercostal space and is sensory for axilla and medial surface of arm
Chp 16: T3-T6 innervate intercostal muscles and are sensory for the anterior chest wall
Chp 16: T7-T12 innervate intercostal muscles, abdominal muscles, and overlying skin
Chp 16: neural tube CNS develops from
Chp 16: neural crest cells cranial and spinal nerves develop from
Chp 16: Neural canal becomes central canal of spinal cord
Chp 16: Basal plates form anterior horns, lateral horns and anterior part of gray commissure
Chp 16: Alar plates form posterior horns and posterior part of gray commissure
Chapter 18: Somatic nervous system (SNS) works on processes that are perceived or consciously controlled
Chp 18: Somatic sensory part involves vision, hearing, touch, proprioception, and so on
Chp 18: Somatic motor part involves control of skeletal muscles
Chp 18: Autonomic nervous system (ANS) is a motor system regulating processes below the conscious level to maintain homeostasis
Chp 18: Autonomic nervous system (ANS) also called also called autonomic (visceral) motor system
Chp 18: Autonomic nervous system (ANS) response: Reflexively responds to visceral sensory inputs (e.g., vessel stretch)
Chp 18: Autonomic nervous system (ANS) sends Sends impulses to cardiac muscle, smooth muscle, and glands
Chp 18: In SNS a single lower motor neuron axon extends from the spinal cord to skeletal muscle fibers The motor neuron has a large myelinated axon and releases acetylcholine to stimulate muscle
Chp 18: has a large myelinated axon and releases acetylcholine to stimulate muscle Preganglionic and ganglionic neurons
Chp 18: The first neuron first neuron in the ANS pathway is the preganglionic neuron; its cell body is in the brain or spinal cord
Chp 18: myelinated preganglionic axon Thin, myelinated preganglionic axon extends to second cell within an autonomic ganglion in peripheral nervous system
Chp 18: The second neuron second neuron is called a ganglionic neuron
Chp 18: unmyelinated postganglionic axon Thin, unmyelinated postganglionic axon extends to effector cells
Chp 18: Two-neuron pathway in ANS allows for greater communication and control due to: - Neuronal convergence: - Neuronal divergence:
Chp 18: Neuronal convergence: Axons from numerous preganglionic cells synapse on a single ganglionic cell
Chp 18: Neuronal divergence: Axons from one preganglionic cell synapse on numerous ganglionic cells
Chp 18: Parasympathetic division - ( help) helps conserve energy and replenish nutrient stores (“rest-and-digest”)
Chp 18: Sympathetic division - (prepares) prepares body for emergencies (“fight- or-flight”); increases alertness and makes nutrients available for use
Chp 18: terminal ganglia close to target organ
Chp 18: intramural ganglia in wall of target organ
Chp 18: There are four cranial nerves associated with the parasympathetic division: – Oculomotor (CN III) – Facial (CN VII) – Glossopharyngeal (CN IX) – Vagus (CN X)
Chp 18: Preganglionic neuron neuron cell bodies are housed within lateral gray regions of S2–S4 spinal cord segments
Chp 18: Preganglionic axons neuron cell bodies are housed within lateral gray regions of S2–S4 spinal cord segments
Chp 18: Preganglionic fibers fibers project to ganglionic neurons within terminal or intramural ganglia of large intestine, rectum, reproductive organs, urinary bladder, and distal ureter
Chp 18: Sympathetic division is also called called the thoracolumbar division
Chp 18: Sympathetic trunks located located anterior to spinal nerves and immediately lateral to vertebral column
Chp 18: Sympathetic trunk ganglia (paravertebral or chain ganglia) housed house sympathetic ganglionic neuron cell bodies; one sympathetic ganglion typically associated with each spinal nerve
Chp 18: Cervical portion portion of each sympathetic trunk is partitioned into the superior, middle, and inferior ganglia
Chp 18: Postganglionic axons from cell bodies axons from cell bodies in superior cervical ganglion distribute to structures in the head and neck
Chp 18: Middle and inferior cervical ganglia house neurons house neurons that extend postganglionic axons to thoracic viscera
Chp 18: Preganglionic sympathetic axons of T1–L2 spinal nerves are carried by white rami communicantes
Chp 18: White rami color reflects myelination
Chp 18: Postganglionic sympathetic axons are carried from sympathetic trunk to spinal nerve by gray rami communicantes
Chp 18: Gray color rami reflects reflects lack of myelin on axons
Chp 18: Gray rami connect connect to all spinal nerves including cervical, sacral, and coccygeal spinal nerves
Chp 18: In crisis situations," mass activation" increases in alertness, energy availability, heart rate, blood pressure, breathing rate and depth
Chp 18: mass activation occurance (simultaneous stimulation of many effectors) occurs
Chp 18: Autonomic plexuses are collections of sympathetic postganglionic axons, parasympathetic preganglionic axons, and visceral sensory axons
Chp 18: Neurotransmitters Acetylcholine (ACh) and norepinephrine (NE)
Chp 18: All preganglionic axons release elease ACh, which has an excitatory effect on the ganglionic cell
Chp 18: ACh-releasing releasing cells are cholinergic neurons
Chp 18: Cholinergic receptors targets target cell bind ACh
Chp 18:All postganglionic parasympathetic axons release ACh on the effector Depending on the type of receptor on the effector, ACh from parasympathetic postganglionic axons may cause excitation or inhibition
Chp 18: Cholinergic receptors are are muscarinic or nicotinic
Chp 18: dual innervation receive input from both the sympathetic and parasympathetic divisions
Chp 18: Antagonistic effects Parasympathetic activity - slows heart; sympathetic activity speeds it up -increases intestinal motility; sympathetic activity decreases it - constricts pupil; sympathetic activity dilates it
Chp 18:Cooperative effects In male sexual response: Parasympathetic activity leads to erection; sympathetic activity leads to ejaculation
Chp 18: CNS Control of Autonomic Function • Autonomic function is influenced by parts of the CNS: -Hypothalamus -Brainstem -Spinal cord
Chp 18: Autonomic function is influenced by parts of the CNS Hypothalamus ntegration center for autonomic nervous system; crucial in emotion; regulates visceral function
Chp 18: Autonomic function is influenced by parts of the CNS Brainstem Brainstem Effects cardiovascular functions, digestive functions, eye’s pupil and lens shape
Chp 18 :Autonomic function is influenced by parts of the CNS Spinal cord Important parasympathetic reflexes for defecation and urination
Chp 18: Neural tube "gives" gives rise to central nervous system components of autonomic nervous system
Chp 18: Neural tubes parts of Parts of hypothalamus, brainstem, spinal cord, white rami
Chp 18: Neural crest gives gives rise to peripheral nervous system components of autonomic nervous system
Chp 18: Neural crest parts of Autonomic ganglia, postganglionic axons, gray rami, adrenal medulla
Created by: Rodney C
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