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Blood Pathologies
Blood Vessel and Blood Pathologies
Term | Definition |
---|---|
Atherosclerosis | Hardening of the arteries |
Arteriosclerosis | Shrinking and loss of elasticity in artery walls |
Polyarteritis nodosa | Autoimmune-caused inflammation of medium and small muscular arteries |
Giant Cell arteritis | Macrophages invade medium sized arteries, most often in temporal region of the head |
Reynaud's disease | Muscular arteries and arterioles constrict rapidly and abnormally |
Hypertension | Causes increased cardiac workload, arteries become worn and positive feedback effect worsens over time |
Varicose Veins | Faulty valves cause veins in lower limbs to become dilated; aggrivated by standing for long periods of time |
Thrombophlebitis | Thrombotic occlusion of the veins preventing outflow of veinous blood and promotes the likelihood of varicosities forming |
Stroke | Caused by cerebral thrombosis, cerebral embolism, and/or burst aneurysms |
Transient Ischemic Attacks | Characterized by sudden, temporary weakness or numbness in face, arm, and/or leg on one side of the body |
Anemia | Blood pathology characterized by reduced hemoglobin levels |
Aplastic Anemia | Generalized bone marrow failure, accompanied by leukopenia and thrombocytopenia |
Iron Deficiency Anemia | Most common form of anemia, causes blood cells to be small and contain less hemoglobin |
Megaloblastic | Due to deficiency of Vitamin B12 or folic acid needed for DNA synthesis and blood cell production |
Hemolytic | Type of anemia due to red blood cell destruction (hemolysis) |
Sickle-cell Anemia | Autosomal dominant disease affecting one of the beta hemoglobin chains |
Polycythemia | Also known as erythrocytosis |
Primary Polycythemia | Due to a malignancy in the red blood cell line; blood becomes viscous leading to hypertension |
Secondary Polycythemia | Non-neoplastic disease due to prolonged hypoxia |
Leukopenia | Reduced number of white blood cells, usually caused by toxins, cancer therapies, or HIV |
Leukocytosis | Increased number of white blood cells; normal response to infection |
Leukemia | Bone marrow contains malignant cells; results in increased leukocytes in blood, anemia, recurrent infections and uncontrolled bleeding |
Lymphoma | Malignancies of lymphocytes and their precursors; accounts for about 3% of all human malignancies |
Non-Hodgkins Lymphoma | Symptoms include lymph node enlargement, systemic problems, tumor spreads to other tissues (e.g., brain) |
Hodgkin's Disease | Malignant lymphoma diagnosed by presence of Reed-Sternberg cells |
Multiple Myeloma | Malignant disease of the plasma cells; most patients over 45 years old |
Hemorrhage | Bleeding disorder; includes three different types: external, internal or purpura |
Purpura | Bleeding from multiple sites |
Thrombocytopenia | Too few platelets; due to aplastic anemia, leukemia, drugs, infectious agents--blood does not clot properly |
Thrombocytosis | Too many platelets; usually due to myeloid malignancy |
Hemophilia | Sex-linked recessive genetic disorder due to lack of factor VIII or XI needed for normal blood clotting |