Hormones from endocrine and CV I/IIR
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| show | Nitric Oxide, vasodilator and inhibitor of platelet aggregation
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| Prostacyclin (PGI2) | show 🗑
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| CD39 (an ADPase) | show 🗑
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| Heparin | show 🗑
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| vWF | show 🗑
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| show | proteins/cytokines that constrict blood vessels
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| show | inactive factor I, fibrin is active factor I, binds to platelet membrane receptor activated by vWF
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| Serotonin (5-HT) | show 🗑
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| ADP | show 🗑
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| show | prostaglandin/eicosinoid, one of three factors in platelet plug formation, vasoconstrictor
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| show | required for thrombus formation, in plasma phase of hemostasis
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| PF3 | show 🗑
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| show | fibrinogen, protein from liver
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| Factor II | show 🗑
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| show | Tissue Factor, lipoprotein from damaged tissue/activated platelets. activates VII, which activates X. enters blood from outside
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| Factor IV | show 🗑
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| Factor V | show 🗑
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| show | no longer used
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| Factor VII | show 🗑
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| Factor VIII | show 🗑
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| Factor IX | show 🗑
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| show | Stuart-Power Factor, protein, from liver requires vitamin K, prothrombinase, where extrinsic and intrinsic pathways meet
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| show | plasma thromboplastin, protein antecedent (PTA), from liver
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| show | Hageman factor, protein, from liver, activated when it contacts subendothelial tissues
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| Factor XIII | show 🗑
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| show | required for liver to synthesize Factors II, VII, IX, X
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| Hemophilia A | show 🗑
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| Hemophilia A | show 🗑
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| show | lack of factor IX, what ended up in the Romanov family
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| Hemophilia C | show 🗑
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| Thrombin | show 🗑
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| show | inhibits many clotting factors, most notably X and II, protein from liver , paired with herparin affect Factors II and X
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| show | membrane protein in endothelial cells, binds with thrombin to decrease level of thrombin and inhibit clotting
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| Protein C | show 🗑
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| Plasmin | show 🗑
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| show | frequently proteolytic enzymes that cleave fibrin and allow trapped cells to escape
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| Aldosterone | show 🗑
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| Cytokines | show 🗑
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| show | tryptophan, tyrosine = catecholamines, peptides. Derived from amino acids
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| show | steroid hormones, eicosinoids
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| show | derivatives of membrane phospholipids , parent molecule is arachidonic acid. Four eicosinoids: prostaglandins, thromboxanes, prostacyclins, leukotrienes
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| Steroid Hormones | show 🗑
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| Phospholipase A | show 🗑
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| Arachidonic Acid | show 🗑
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| Cyclooxygenases | show 🗑
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| Lipoxygenase | show 🗑
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| Leukotrienes | show 🗑
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| show | functional <1 hour, usually not complexed with transport protein, quickly degraded: hydrophilic, lipophobic, and polar. not membrane diffusable
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| show | circulate much longer, >99% become attached to transport protein thus larger reserve in blood: hydrophobic, lipophilic, and nonpolar. membrane diffusable
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| show | from parathyroid principle (chief) cells, increases Ca++ blood concentration, targets kidney, and bone
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| Melatonin | show 🗑
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| show | peptide neurohormone, known as vasopressin, from posterior pituitary, targets kidney for blood volume and pressure
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| Oxytocin | show 🗑
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| Tropic Hormones | show 🗑
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| Six Hormones from Anterior Pituitary | show 🗑
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| Thyroglobulin | show 🗑
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| T3 | show 🗑
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| T4 | show 🗑
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| show | transports T3
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| Calcitonin | show 🗑
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| show | adrencorticotropic hormone, targets adrenal gland zona fasciculata, increases cortisol
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| Cortisol | show 🗑
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| show | corticotropin releasing hormone, stimulates ACTH to go to kidney to increase cortisol
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| show | dehydroepiandrosterone, primary androgen secreted by zona reticularis, a steroid precursor to testosterone, calls for secondary sex characteristics in males
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| show | somatotropin, direct effects are anabolic, releasing energy, and stimulating growth, indirect effects mediated by somatomedins
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| show | liver hormones stimulated by hGH
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| show | insulin-like growth factor, most important somatomedin, associated with osteogenesis, strong effect on cartilage, bone, and skeletal muscle growth
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| LH | show 🗑
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| show | follicle stimulating hormone, gamete production ova/sperm, target seminiferous tubule nurse cells in males, meiotic divisions for haploid sperm
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| show | maintaining partitioning of water between plasma and interstitial fluid
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| show | enzymatic activity and/or are transport proteins, made in liver
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| Gamma globulins | show 🗑
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| show | protein A2B2 polypeptide chains and 4 heme groups
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| show | erythropoieton, made by peritubular fibroblasts of the renal cortex, regulating RBC numbers, causing myeloid stem cells to turn into RBCs
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| show | transports Fe in and out of the liver
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| Bilirubin | show 🗑
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| Bile | show 🗑
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