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A&P II: Heart&Blood
Mod 4
Question | Answer |
---|---|
cardiac output = | Heart rate/minute x mL/beat |
stroke volume = | mL/beat or EDV - ESV |
cardiac output | amount of blood pumped out by each ventricle in one minute average 75/minute |
stroke volume | amount of blood pumped by each ventricle with each heartbeat average 70 mL/beat |
end diastolic volume | amount of blood in each ventricle at the end of diastole (relaxation) |
end stroke volume | amount of blood in each ventricle at the end of systole (contraction) |
stroke volume = | EDV - ESV |
How does a drop in BP affect the heart rate? | low BP Increases stroke volume (SNS) |
How does a drop in blood volume affect the heart rate? | low blood volume Increases stroke volume (SNS) |
How does fright affect the heart rate? | Increases stroke volume (SNS) |
How does a crisis averted affect the heart rate? | Decreases stroke volume (PNS) |
composed of cardiac muscle tissue | myocardium |
visceral pericardium, simple squamous epithelium | epicardium |
smooth inner lining of the heart, simple squamous epithelium | endocardium |
another name for epicardium | visceral pericardium |
form a double layer sac around the heart | visceral and fibrous pericardium |
serous membrane of the heart (two) | visceral and parietal pericardium |
fibrous connective tissue attached to diaphragm and base of great vessels | fibrous pericardium |
forms pericardial cavity filled with percardial fluid acting as a lubricant during heart contraction | visceral and parietal pericardium |
the left ventricle pumps to the systemic circulation through the | aorta |
the right ventricle pumps pulmonary circulation through the | pulmonary trunk |
blood returning from the systemic circulation enters the | right side |
blood returning from the pulmonary circulation enters the | left side |
pulmonary trunk exits this chamber | right ventricle |
vena cavae enter this chamber | right atrium |
tricuspid valve connects these chambers | right atrium and right ventricle |
bicuspid valve conects these chambers | left atrium and left ventricle |
aorta exits this chamber | left ventricle |
pulmonary veins enter this chamber | left atrium |
form pump for pulmonary circulation | right ventricle |
form pump for systemic circulation | left ventricle |
general function of valves of the heart | prevent backflow |
where is the aortic semilunar valve | left ventricle |
where is the pulmonary semilunar valve | right ventricle |
how is the structure of the atrioventricular valve different from the semilunar valve | semilunar is more like a pocket |
blood vessels supplying the heart muscle | coronary arteries |
vein returning blood from the heart wall | coronary sinus |
where are the coronary arteries located | coronary sulcus on the posterior surface of the heart |
where does blood from the coronary arteries go? | right atrium |
cardiac muscle innervation | ANS |
skeletal muscle innervation | SNS |
cardiac muscle stimulus for contraction | autorhythmic neuron |
skeletal muscle stimulus for contraction | somatic neuron |
made of desmosomes and gap junctions | intercalated discs |
allow muscle potentials to conduct from one muscle fiber to neighbor (no chemical neurotransmitters) | gap junction |
holds muscle fibers together | desmosomes |
action potential is longer/shorter for cardiac muscle than skeletal muscle | longer |
ions involved in cardiac muscle depolarization | Na+ and Ca2+ |
what ion maintains depolarization so cardiac muscle can relax | Ca2+ |
what are 2 sources for cardiac muscle Ca2+ | ISF and SR |
what is one source for skeletal muscle Ca+ | SR |
tetanus can/cannot happen in cardiac muscle | cannot |
another contraction can/can't happen until relaxation of the heart muscle | can't |
True/False: autorhythmic fibers form a conduction system of the skeletal muscle | False |
sinoatrial node is also known as the ________ of the heart | pacemaker |
True/False: the pacemaker potential is spontaneous depolarization | True |
True/False: an action potential starts in the AV node of the heart | False |
True/False: AP - SA node - AV node - AV bundle - Bundle Branches - Purkinje fibers | True |
what fibers surround the apex of the heart causing contraction of the ventricles | Purkinje fibers |
what part of the conduction system serves as the pacemaker | SA node |
what is the only electrical connection between the atrial and ventricular muscle masses | AV bundle |
True/False: electrical conduction through the AV node is fast | Fast |
True/False: slow conduction thru the AV node give ventricles time to finish filling before contracting | True |
Rapid conduction of Purkinje fibers affects blood pressure and | coordination |
any abnormality in the rhythm of the heart (too fast or too slow) is called | arrhythmia |
phase of contraction of the heart muscle, especially the ventricles | systole |
phase of relaxation of the heart muscle, especially the ventricles | diastole |
True/False: during diastole, both the atria and ventricles relax | True |
During diastole blood is flowing from the _______into the atria. | veins |
During diastole, blood is flowing from the atria into the ______. | ventricles |
Atrial systole is intiated by | SA node causes depolarization |
Atrial systole is preceded by the _______ wave of the EKG. | P |
The atria contract/relax during atrial systole. | contract |
During atrial systole, blood flows from the ______ to the ventricles. | atria |
Ventricular systole is preceded by the ________ wave of the EKG. | QRS |
What is the advantage of atrial systole? more time for ventricular filling = | more efficient filling |
this is occurs for a brief moment before the SL valves open and the AV valves are closed | isovolumetric contraction |
this occurs for a brief moment before the AV valves open and the SL valves are closed | isovolumetric relaxation |
AV valves close ventricular pressure is greater/lesser than atrial pressure | greater |
SL valves close when ventricular pressure is greater/lesser than aortic pressure | lesser |
the volume remaining in each ventricle at the end of systole, about 60 mL | ESV |
the volume remaining in each ventricle at the end of diastole | EDV |
the amount of blood leaving the heart during systole (SV/EDV x 100 = EF) | ejection fraction |
diastole is known as the pumping/filling stage of the cardiac cycle | filling |
During what event(s) are the AV valves open and SL valves closed? | ventricular diastole and atrial systole |
At the beginning of ventricular systole, which valves open and which valves close? | SL open and AV close |
At the beginning of atrial systole, which valves open and which valves close? | AV open and SL close |
If you hear an abnormal first heart sound, which valves would it be? | AV valve during ventricular systole |
In a heart murmur, valves do not completely ________. | close |
The second heart sound is due to the _______ closing during ventricular diastole. | SL valves |
Name this rule: The greater the stretch of the heart muscle, the greater the contraction. | Frank-Starling Law of the Heart |
the volume of blood returning to the ventricles via the atria via the veins | venous return |
more venous return = more blood = better ventricular filling = greater EDV | greater stroke volume |
substances that increase or decrease contractility | inotropic effect |
every other factor other than preload on the strength of contraction | contractility |
the vasopressure that must be overcome before an SL valve can open | afterload |
increased afterload equals | decreased stroke volume |
"filling stage": proportional to EDV, the degree of stretch before the heart contracts | preload |
The SA node does/does not require outside stimulation to initiate a heartbeat. | does not |
Rate of SA node firing can be modified by two factors: ANS and _______. | hormones |
SNS stimulation increases | heart rate |
PNS stimulation decreases | heart rate |
How does the hormone epinephrine affect heart rate? | increases frequency |
An abnormally rapid heart rate causes less ventricular filling time, causes decreased EDV, causes | decreased SV |
cardiac control centers are located in the ____________ of the brain | medulla oblongata |
SNS post-ganglionic axons release the neurotransmitter | norepinephrine |
PNS post-ganglionic axons release the neurotransmitter | acetylcholine |
increase the firing of the SA node | SNS |
decrease the firing of the SA node | PNS |
PNS ______ is responsible for slowing the heart rate down | vagal tone |
PNS is associated with the | vagus nerve |
When SNS releases something that increases the stroke volume, it is called a | positive inotropic effect |
PNS causes a decrease in | cardiac output |
only blood vessel layer of capillary walls, direct contact with lumen, simple squamous epithelium | tunica intima |
tunica intima AKA | endothelium |
blood vessel layer contains smooth muscle and elastic connective tissue | tunica media |
blood vessel layer consists of fibrous connective tissue | tunica externa |
smallest artery; greatest proportion of smooth muscle; "resistance vessels" | arterioles |
vessels with intercellular clefts for exchange between plasma & ISF | capillaries |
vessels with valves that act as a "volume reservoir" for blood | veins |
capillaries consist of simple __________ epithelium | squamous |
arterioles are/are not capable of significant vasoconstriction and vasodilation | are |
smallest vein | venule |
most capillaries plasma membranes of ________ cells that form a continuous tube | epithelial |
capillaries with small pores in the plasma membrane | fenestrated |
wide & winding capillaries containing specialized lining cells & intercellular clefts | sinusoids |
hydrostatic (fluid) pressure exerting blood on the walls of a blood vessel | blood pressure |
The driving ____ for blood flow is BP generated by contracting ventricles & maintained by stretch & recoil of artery walls. | force |
blood pressure refers to the BP in arteries in _________ circulation | systemic |
blood pressure increases, ________ increases | blood flow |
Blood flow is driven by the blood pressure gradient, but it is opposed by | vascular resistance |
The force exerted by blood on arterial walls during ventricular contraction is | systolic blood pressure |
The force exerted by blood on arterial walls during ventricular relaxation is | diastolic blood pressure |
The average BP in the arteries | MAP |
MAP | mean arterial blood pressure |
the difference between systolic and diastolic pressure | pulse pressure |
a traveling pressure wave of alternating expansion & recoil of elastic arteries | pulse |
2 factors to vascular resistance: vessel lumen diameter and vessel ________ | length |
2 factors to peripheral resistance: vascular resistance and blood ________ | viscosity |
most important variable of peripheral resistance | diameter of lumen |
diameter of lumen of arterioles is the most/least significant factor of PR | most |
widening of vessel diameter due to smooth muscle relaxation | vasodilation |
narrowing of vessel diameter due to smooth muscle contraction | vasocontraction |
Systemic changes are ________ body changes. | whole |
Systemic blood pressure is generally regulated by: | SNS & hormones |
Changes in arterioles and pre-capillary sphincters supplying a specific tissue regulates flow to individual capillary beds. | autoregulation |
Autoregulation is regulated by local ________ factors. | metabolic |
Arteriole diameter is regulated by the ________ nervous system. | sympathetic |
Arterioles are slightly constricted constantly by constant discharge of the sympathetic nervous system. | vasomotortone |
center in the medulla oblongata which regulates vasoconstriction and vasodilation | vasomotor |
in medulla oblongata: vasomotor, cardioaccelerator, & cardioinhibitory centers make up the | cardiovascular center |
Autoregulation is influenced by local metabolic factors and | heat |
ephinephrine dilates | coronary vessels |
norepinephrine causes/prevents vasoconstriction | causes |
which blood components cannot normally exit capillaries? | proteins & RBC's |
4 structures of capillaries promote ISF/plasma exchange: thin membranes, endothelial cells, pinocytic cells, and | intercellular clefts |
movement of dissolved molecules in response to concentration gradient | diffusion |
molecules that diffuse across capillary walls include, CO2, glucose, some hormones and | O2 |
large lipids & lipid soluble molecules transfer to capillaries via pinocytic vescicles called | transcytosis |
movement of water and small molecules in response to a pressure gradient is called | bulk flow |
bulk flow is an important factor in maintaining the balance of ___ in blood & ISF | water |
bulk flow occurs by filtration and | reabsorption |
Direction of bulk flow across capillary walls is determined by _____ across the wall. | net pressure gradient |
Blood hydrostatic pressure within the capillary favors flow _____ of the capillary. | out |
Blood colloidal osmotic pressure or osmotic draw favors flow into/out of the capillary. | into |
Blood is hypertonic/hypotonic to the ISF because of proteins | hypertonic |
water travels to the greater concentration of solute due to | osmosis |
hydrostatic pressure causing fluid flow in & osmotic pressure causing fluid flow out of capillaries is also known as | Starling's law of the capillaries |
lower than normal concentration of plasma proteins leads to increased ISF & decreased | blood volume |
increased capillary pressure due to poor venous return leads to increased ISF & | decreased BV |
blockage of lymphatic circulation leads to lower blood volume and higher | ISF |
structure that prevents backflow of blood within most veins | venous valve |
contraction of skeletal muscle compresses the vein slowing and reducing venous | return |
venodilation increases | venous return |
venoconstriction decreases _________ return | venous |
Mean Arteriole Pressure equals Cardiac Output times ________. | Peripheral Resistance |
Either Cardiac Output or Peripheral Resistance or both homeostatically regulate | arterial blood pressure |
Homeostatic regulation of arterial pressure is accomplished through the | baroreceptor reflex |
baroreceptor reflex receptors detect stretch in the walls of the aortic arch and | carotid sinus |
the integration center for the baroreceptor reflex is located in | the cardiovascular center of the medulla oblongata |
The efferent pathway for the baroreceptor reflex if along the ANS and | motor neurons. |
The effectors for this reflex are the myocardium and _______ of arterioles & veins. | smooth muscle |
Arterioles dilate to correct ______ blood pressure. | high |
Heart rate increases to correct _______ blood pressure. | low |
_________ resistance increases to correct blood pressure. | Peripheral |
Stroke ________ decreases to correct high blood pressure. | volume |
Veins constrict/dilate to correct low blood pressure. | constrict |
Cardiac _____ decreases to correct high blood pressure. | output |